Exploring Scrotal Leiomyomas, Unraveling the Mysteries of a Rare Tumor: A Case Report
Leiomyomas, originating from smooth muscle cells, are common in the uterus but rare in the scrotum, presenting a clinical challenge. Scrotal leiomyomas, first described in the 19th century, are characterized by benign pathology from the subcutaneous dartos muscle. We present two cases of middl...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Asian Medical Press Ltd.(H.K.)
2024-01-01
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| Series: | Annals of Urologic Oncology |
| Subjects: | |
| Online Access: | http://auo.asmepress.com/articles/new-56-663.html |
| _version_ | 1797338692573986816 |
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| author | Sana Ahuja Pooja Verma Adil Aziz Khan Sufian Zaheer |
| author_facet | Sana Ahuja Pooja Verma Adil Aziz Khan Sufian Zaheer |
| author_sort | Sana Ahuja |
| collection | DOAJ |
| description | Leiomyomas, originating from smooth muscle cells, are common in the uterus but rare in
the scrotum, presenting a clinical challenge. Scrotal leiomyomas, first described in the 19th
century, are characterized by benign pathology from the subcutaneous dartos muscle.
We present two cases of middle-aged males with scrotal leiomyomas, detailing clinical
presentations, histopathological findings, and immunohistochemistry results. The first involved
a 48-year-old with a painless scrotal lump, excised to reveal well-circumscribed smooth
muscle bundles. Immunohistochemistry confirmed vimentin, desmin, and smooth muscle
actin (SMA) positivity, consistent with scrotal leiomyoma. The second case featured a 25-yearold with a painless scrotal swelling, histologically matching the features of scrotal leiomyoma.
Accurate diagnosis is crucial for guiding appropriate management strategies. Clinicians
often employ a combination of clinical evaluation, imaging studies, and histopathological
examination to confirm the presence of scrotal leiomyomas. Ultrasound remains a valuable
tool for assessing the size, location, and vascularity of the tumor, aiding in the formulation of a
differential diagnosis. Definitive diagnosis, however, relies on histological examination, which
typically reveals spindle-shaped smooth muscle cells arranged in interlacing bundles. |
| first_indexed | 2024-03-08T09:34:55Z |
| format | Article |
| id | doaj.art-75190c5b64dc4ebca0942dc20b677836 |
| institution | Directory Open Access Journal |
| issn | 2617-7765 2617-7773 |
| language | English |
| last_indexed | 2024-03-08T09:34:55Z |
| publishDate | 2024-01-01 |
| publisher | Asian Medical Press Ltd.(H.K.) |
| record_format | Article |
| series | Annals of Urologic Oncology |
| spelling | doaj.art-75190c5b64dc4ebca0942dc20b6778362024-01-30T09:51:38ZengAsian Medical Press Ltd.(H.K.)Annals of Urologic Oncology2617-77652617-77732024-01-0171510.32948/auo.2024.01.28Exploring Scrotal Leiomyomas, Unraveling the Mysteries of a Rare Tumor: A Case ReportSana Ahuja0Pooja Verma1 Adil Aziz Khan2Sufian Zaheer3Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, IndiaDepartment of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.Leiomyomas, originating from smooth muscle cells, are common in the uterus but rare in the scrotum, presenting a clinical challenge. Scrotal leiomyomas, first described in the 19th century, are characterized by benign pathology from the subcutaneous dartos muscle. We present two cases of middle-aged males with scrotal leiomyomas, detailing clinical presentations, histopathological findings, and immunohistochemistry results. The first involved a 48-year-old with a painless scrotal lump, excised to reveal well-circumscribed smooth muscle bundles. Immunohistochemistry confirmed vimentin, desmin, and smooth muscle actin (SMA) positivity, consistent with scrotal leiomyoma. The second case featured a 25-yearold with a painless scrotal swelling, histologically matching the features of scrotal leiomyoma. Accurate diagnosis is crucial for guiding appropriate management strategies. Clinicians often employ a combination of clinical evaluation, imaging studies, and histopathological examination to confirm the presence of scrotal leiomyomas. Ultrasound remains a valuable tool for assessing the size, location, and vascularity of the tumor, aiding in the formulation of a differential diagnosis. Definitive diagnosis, however, relies on histological examination, which typically reveals spindle-shaped smooth muscle cells arranged in interlacing bundles.http://auo.asmepress.com/articles/new-56-663.htmlscrotalleiomyomasebaceous cystmesenchymal |
| spellingShingle | Sana Ahuja Pooja Verma Adil Aziz Khan Sufian Zaheer Exploring Scrotal Leiomyomas, Unraveling the Mysteries of a Rare Tumor: A Case Report Annals of Urologic Oncology scrotal leiomyoma sebaceous cyst mesenchymal |
| title | Exploring Scrotal Leiomyomas, Unraveling the Mysteries of a Rare Tumor: A Case Report |
| title_full | Exploring Scrotal Leiomyomas, Unraveling the Mysteries of a Rare Tumor: A Case Report |
| title_fullStr | Exploring Scrotal Leiomyomas, Unraveling the Mysteries of a Rare Tumor: A Case Report |
| title_full_unstemmed | Exploring Scrotal Leiomyomas, Unraveling the Mysteries of a Rare Tumor: A Case Report |
| title_short | Exploring Scrotal Leiomyomas, Unraveling the Mysteries of a Rare Tumor: A Case Report |
| title_sort | exploring scrotal leiomyomas unraveling the mysteries of a rare tumor a case report |
| topic | scrotal leiomyoma sebaceous cyst mesenchymal |
| url | http://auo.asmepress.com/articles/new-56-663.html |
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