Immunological efficacy of glypican-3 peptide vaccine in patients with advanced hepatocellular carcinoma

Immunological efficacy of glypican-3 peptide vaccine in patients with advanced hepatocellular carcinoma

We have previously conducted a phase I trial to test the efficacy of a glypican-3 (GPC3) peptide vaccine in patients with advanced hepatocellular carcinoma (HCC); however, its immunological mechanism of action remains unclear. Here, we report a pilot study conducted to evaluate the immunological mec...

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Bibliographic Details
Main Authors: Nobuhiro Tsuchiya, Toshiaki Yoshikawa, Norihiro Fujinami, Keigo Saito, Shoichi Mizuno, Yu Sawada, Itaru Endo, Tetsuya Nakatsura
Format: Article
Language:English
Published: Taylor & Francis Group 2017-10-01
Series:OncoImmunology
Subjects:
peptide vaccine
glypican-3 (gpc3)
ctl
hcc
immunological efficacy
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1346764

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