Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China
Background To analyze the health-related quality of life associated with the conversion of dialysis modality among end-stage renal disease patients in China. Methods Patients were recruited from hospitals and a dialysis center in Kunshan, China. Patients converting from continuous ambulatory periton...
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PeerJ Inc.
2022-01-01
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| author | Heqi Sun Ye Zhuang Lanying Gao Ningze Xu Yan Xiong Min Yuan Jun Lu Jianming Ye |
| author_facet | Heqi Sun Ye Zhuang Lanying Gao Ningze Xu Yan Xiong Min Yuan Jun Lu Jianming Ye |
| author_sort | Heqi Sun |
| collection | DOAJ |
| description | Background To analyze the health-related quality of life associated with the conversion of dialysis modality among end-stage renal disease patients in China. Methods Patients were recruited from hospitals and a dialysis center in Kunshan, China. Patients converting from continuous ambulatory peritoneal dialysis to automated peritoneal dialysis were recruited as the observation group (n = 64), and patients continuing with continuous ambulatory peritoneal dialysis treatment were included in the control group (n = 64) after matching in this retrospective cohort study. Their health-related quality of life was measured using the kidney disease quality of life instrument in 2019 and 2020, respectively. Baseline socio-demographic characteristics and clinical data were collected in 2019. The before-and-after cross-group comparisons of subscale scores of two groups were conducted using a Student‘s t-test. Multiple linear regression models were fitted to identify the factors associated with the change of each scale. Results The health-related quality of life scores of the two groups was comparable in baseline, while the observation group had higher scores in Physical Component Summary (51.92 ± 7.50), Kidney Disease Component Summary (81.21 ± 8.41), Symptoms (90.76 ± 6.30), Effects (82.86 ± 11.42), and Burden (69.04 ± 15.69) subscales after one year. In multivariate regression analysis, the change of Physical Component Summary was significantly associated with conversion to APD (β = 11.54, 95% CI [7.26–15.82]); the change of Mental Component Summary with higher education (β = − 5.96, 95% CI [−10.18–−1.74]) and CCI (>2) (β = 5.39, 95% CI [1.05–9.73]); the change of Kidney Disease Component Summary with conversion to APD (β = 15.95, 95% CI [10.19–21.7]) and age (>60 years) (β = − 7.36, 95% CI [−14.11–−0.61]); the change of Symptoms with CCI (>2) (β = 7.96, 95% CI [1.49–14.44]); the change of Effects with conversion to APD (β = 19.23, 95% CI [11.57–26.88]); and the change of Burden with conversion to APD (β = 22.40, 95% CI [13.46–31.34]), age (>60 years) (β = − 12.12, 95% CI [−22.59–−1.65]), and higher education (β = − 10.38, 95% CI [−19.79–−0.98]). Conclusions The conversion of dialysis modality had a significant impact on the scores of most subscales. Patients converting from continuous ambulatory peritoneal dialysis to automated peritoneal dialysis generally had improved health-related quality of life scores. |
| first_indexed | 2024-03-09T06:35:12Z |
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| spelling | doaj.art-751e1981773f4bed844a847657d9e8b42023-12-03T10:59:48ZengPeerJ Inc.PeerJ2167-83592022-01-0110e1279310.7717/peerj.12793Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in ChinaHeqi Sun0Ye Zhuang1Lanying Gao2Ningze Xu3Yan Xiong4Min Yuan5Jun Lu6Jianming Ye7School of Public Health, Fudan University, Shanghai, ChinaSchool of Public Health, Fudan University, Shanghai, ChinaDepartment of Nephrology, The First People’s Hospital of Kunshan, Suzhou, ChinaSchool of Public Health, Fudan University, Shanghai, ChinaDepartment of Nephrology, The First People’s Hospital of Kunshan, Suzhou, ChinaSchool of Public Health, Fudan University, Shanghai, ChinaSchool of Public Health, Fudan University, Shanghai, ChinaDepartment of Nephrology, The First People’s Hospital of Kunshan, Suzhou, ChinaBackground To analyze the health-related quality of life associated with the conversion of dialysis modality among end-stage renal disease patients in China. Methods Patients were recruited from hospitals and a dialysis center in Kunshan, China. Patients converting from continuous ambulatory peritoneal dialysis to automated peritoneal dialysis were recruited as the observation group (n = 64), and patients continuing with continuous ambulatory peritoneal dialysis treatment were included in the control group (n = 64) after matching in this retrospective cohort study. Their health-related quality of life was measured using the kidney disease quality of life instrument in 2019 and 2020, respectively. Baseline socio-demographic characteristics and clinical data were collected in 2019. The before-and-after cross-group comparisons of subscale scores of two groups were conducted using a Student‘s t-test. Multiple linear regression models were fitted to identify the factors associated with the change of each scale. Results The health-related quality of life scores of the two groups was comparable in baseline, while the observation group had higher scores in Physical Component Summary (51.92 ± 7.50), Kidney Disease Component Summary (81.21 ± 8.41), Symptoms (90.76 ± 6.30), Effects (82.86 ± 11.42), and Burden (69.04 ± 15.69) subscales after one year. In multivariate regression analysis, the change of Physical Component Summary was significantly associated with conversion to APD (β = 11.54, 95% CI [7.26–15.82]); the change of Mental Component Summary with higher education (β = − 5.96, 95% CI [−10.18–−1.74]) and CCI (>2) (β = 5.39, 95% CI [1.05–9.73]); the change of Kidney Disease Component Summary with conversion to APD (β = 15.95, 95% CI [10.19–21.7]) and age (>60 years) (β = − 7.36, 95% CI [−14.11–−0.61]); the change of Symptoms with CCI (>2) (β = 7.96, 95% CI [1.49–14.44]); the change of Effects with conversion to APD (β = 19.23, 95% CI [11.57–26.88]); and the change of Burden with conversion to APD (β = 22.40, 95% CI [13.46–31.34]), age (>60 years) (β = − 12.12, 95% CI [−22.59–−1.65]), and higher education (β = − 10.38, 95% CI [−19.79–−0.98]). Conclusions The conversion of dialysis modality had a significant impact on the scores of most subscales. Patients converting from continuous ambulatory peritoneal dialysis to automated peritoneal dialysis generally had improved health-related quality of life scores.https://peerj.com/articles/12793.pdfEnd-stage renal diseaseAutomated peritoneal dialysisContinuous ambulatory peritoneal dialysisHealth-related quality of lifeDialysis modality conversion |
| spellingShingle | Heqi Sun Ye Zhuang Lanying Gao Ningze Xu Yan Xiong Min Yuan Jun Lu Jianming Ye Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China PeerJ End-stage renal disease Automated peritoneal dialysis Continuous ambulatory peritoneal dialysis Health-related quality of life Dialysis modality conversion |
| title | Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China |
| title_full | Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China |
| title_fullStr | Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China |
| title_full_unstemmed | Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China |
| title_short | Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China |
| title_sort | impact of dialysis modality conversion on the health related quality of life of peritoneal dialysis patients a retrospective cohort study in china |
| topic | End-stage renal disease Automated peritoneal dialysis Continuous ambulatory peritoneal dialysis Health-related quality of life Dialysis modality conversion |
| url | https://peerj.com/articles/12793.pdf |
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