High iron-mediated increased oral fungal burden, oral-to-gut transmission, and changes to pathogenicity of Candida albicans in oropharyngeal candidiasis

High iron-mediated increased oral fungal burden, oral-to-gut transmission, and changes to pathogenicity of Candida albicans in oropharyngeal candidiasis

Background Iron affects the diversity of the oral microbial landscape. Laboratory-strain CAI4 of Candida albicans that causes oropharyngeal candidiasis (OPC) exhibits iron-induced changes to the cell wall, impacting phagocytosis (by macrophages) and susceptibility of fungal cells to cell wall-pertur...

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Bibliographic Details
Main Authors: Aparna Tripathi, Anubhav Nahar, Rishabh Sharma, Trevor Kanaskie, Nezar Al-Hebshi, Sumant Puri
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Journal of Oral Microbiology
Subjects:
Candida albicans
oropharyngeal candidiasis
iron
antifungal-resistance
cell wall
β-1
Online Access:https://www.tandfonline.com/doi/10.1080/20002297.2022.2044110

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