Comparison of the on-line effects of different motor simulation conditions on corticospinal excitability in healthy participants
Abstract In healthy participants, corticospinal excitability is known to increase during motor simulations such as motor imagery (MI), action observation (AO) and mirror therapy (MT), suggesting their interest to promote plasticity in neurorehabilitation. Further comparing these methods and investig...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-06-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-92591-4 |
| _version_ | 1818435207784562688 |
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| author | C. Pfenninger S. Grosprêtre A. Remontet T. Lapole |
| author_facet | C. Pfenninger S. Grosprêtre A. Remontet T. Lapole |
| author_sort | C. Pfenninger |
| collection | DOAJ |
| description | Abstract In healthy participants, corticospinal excitability is known to increase during motor simulations such as motor imagery (MI), action observation (AO) and mirror therapy (MT), suggesting their interest to promote plasticity in neurorehabilitation. Further comparing these methods and investigating their combination may potentially provide clues to optimize their use in patients. To this end, we compared in 18 healthy participants abductor pollicis brevis (APB) corticospinal excitability during MI, AO or MT, as well as MI combined with either AO or MT. In each condition, 15 motor-evoked potentials (MEPs) and three maximal M-wave were elicited in the right APB. Compared to the control condition, mean normalized MEP amplitude (i.e. MEP/M) increased during MI (P = .003), MT (P < .001) and MT + MI (P < .001), without any difference between the three conditions. No MEP modulation was evidenced during AO or AO + MI. Because MI provided no additional influence when combined with AO or MT, our results may suggest that, in healthy subjects, visual feedback and unilateral movement with a mirror may provide the greatest effects among all the tested motor simulations. |
| first_indexed | 2024-12-14T16:49:13Z |
| format | Article |
| id | doaj.art-7521f23281234657829265d812f3b66e |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-14T16:49:13Z |
| publishDate | 2021-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-7521f23281234657829265d812f3b66e2022-12-21T22:54:06ZengNature PortfolioScientific Reports2045-23222021-06-011111810.1038/s41598-021-92591-4Comparison of the on-line effects of different motor simulation conditions on corticospinal excitability in healthy participantsC. Pfenninger0S. Grosprêtre1A. Remontet2T. Lapole3Univ Lyon, UJM-Saint-Etienne, Inter-university Laboratory of Human Movement Biology, EA 7424Univ Bourgogne Franche Comté, Culture, Sport, Health, Society, EA 4660 C3SUniv Lyon, UJM-Saint-Etienne, Inter-university Laboratory of Human Movement Biology, EA 7424Univ Lyon, UJM-Saint-Etienne, Inter-university Laboratory of Human Movement Biology, EA 7424Abstract In healthy participants, corticospinal excitability is known to increase during motor simulations such as motor imagery (MI), action observation (AO) and mirror therapy (MT), suggesting their interest to promote plasticity in neurorehabilitation. Further comparing these methods and investigating their combination may potentially provide clues to optimize their use in patients. To this end, we compared in 18 healthy participants abductor pollicis brevis (APB) corticospinal excitability during MI, AO or MT, as well as MI combined with either AO or MT. In each condition, 15 motor-evoked potentials (MEPs) and three maximal M-wave were elicited in the right APB. Compared to the control condition, mean normalized MEP amplitude (i.e. MEP/M) increased during MI (P = .003), MT (P < .001) and MT + MI (P < .001), without any difference between the three conditions. No MEP modulation was evidenced during AO or AO + MI. Because MI provided no additional influence when combined with AO or MT, our results may suggest that, in healthy subjects, visual feedback and unilateral movement with a mirror may provide the greatest effects among all the tested motor simulations.https://doi.org/10.1038/s41598-021-92591-4 |
| spellingShingle | C. Pfenninger S. Grosprêtre A. Remontet T. Lapole Comparison of the on-line effects of different motor simulation conditions on corticospinal excitability in healthy participants Scientific Reports |
| title | Comparison of the on-line effects of different motor simulation conditions on corticospinal excitability in healthy participants |
| title_full | Comparison of the on-line effects of different motor simulation conditions on corticospinal excitability in healthy participants |
| title_fullStr | Comparison of the on-line effects of different motor simulation conditions on corticospinal excitability in healthy participants |
| title_full_unstemmed | Comparison of the on-line effects of different motor simulation conditions on corticospinal excitability in healthy participants |
| title_short | Comparison of the on-line effects of different motor simulation conditions on corticospinal excitability in healthy participants |
| title_sort | comparison of the on line effects of different motor simulation conditions on corticospinal excitability in healthy participants |
| url | https://doi.org/10.1038/s41598-021-92591-4 |
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