Changes in Collagen Type 3, Elastin, Fibrosis and Cajal Cell in Congenital Ureteropelvic Junction Obstruction
To compare changes in collagen type 3, elastin, fibrosis and cajal cells through histopathological examination of the ureteropelvic junction (UPJ) segments of pediatric and adult patients who had undergone AndersonHynes pyeloplasty for ureteropelvic junction obstruction (UPJO). Materials and Met...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2014-11-01
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| Series: | Journal of Urological Surgery |
| Subjects: | |
| Online Access: | http://jurolsurgery.org/article_7424/Changes-In-Collagen-Type-3-Elastin-Fibrosis-And-Cajal-Cell-In-Congenital-Ureteropelvic-Junction-Obstruction |
| _version_ | 1828030152503721984 |
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| author | Hasan Deliktaş Oktay Issı Abdullah Gedik Hayrettin Şahin |
| author_facet | Hasan Deliktaş Oktay Issı Abdullah Gedik Hayrettin Şahin |
| author_sort | Hasan Deliktaş |
| collection | DOAJ |
| description | To compare changes in collagen type 3, elastin, fibrosis and cajal cells
through histopathological examination of the ureteropelvic junction (UPJ)
segments of pediatric and adult patients who had undergone AndersonHynes
pyeloplasty for ureteropelvic junction obstruction (UPJO).
Materials and Methods
Histopathological evaluation was made of the UPJ segments of 52 patients
who underwent Anderson-Hynes pyeloplasty for UPJO between January
2005 and January 2008. Patients were separated into 2 groups as pediatric,
aged ≤15 years (group 1, n=10) and adult, aged >15 years (group 2, n=42).
UPJ segments of both groups were compared histopathologically (collagen
type 3, elastin, fibrosis and cajal cells). Radiographic evaluations were made
with diuretic renogram and/or intravenous pyelography.
Results
Mean age of group 1 patients was 8.12±2.6 years (1-12 years) and of group
2 patients, 38.16±5.91 years (16-62 years). Mean follow-up period was 18
months (9-24 months). No statistically significant difference was determined
between the groups in respect of collagen type 3, elastin, fibrosis or cajal
cells (p>0.05).
Conclusion
As the pathology in the UPJ obstruction is a congenital defect, the
histopathology does not change with age. |
| first_indexed | 2024-04-10T14:22:52Z |
| format | Article |
| id | doaj.art-752208883b914346afcdb0e16c72027a |
| institution | Directory Open Access Journal |
| issn | 2148-9580 |
| language | English |
| last_indexed | 2024-04-10T14:22:52Z |
| publishDate | 2014-11-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Journal of Urological Surgery |
| spelling | doaj.art-752208883b914346afcdb0e16c72027a2023-02-15T16:09:14ZengGalenos YayineviJournal of Urological Surgery2148-95802014-11-0111111310.4274/jus.112Changes in Collagen Type 3, Elastin, Fibrosis and Cajal Cell in Congenital Ureteropelvic Junction ObstructionHasan Deliktaş0Oktay Issı1Abdullah Gedik2Hayrettin Şahin3Muğla Sıtkı Koçman University Faculty of Medicine, Department of Urology, Muğla, TurkeyBingöl State Hospital, Clinic of Urology, Bingöl, TurkeyDicle University Faculty of Medicine, Department of Urology, Diyarbakır, TurkeyMuğla Sıtkı Koçman University Faculty of Medicine, Department of Urology, Muğla, TurkeyTo compare changes in collagen type 3, elastin, fibrosis and cajal cells through histopathological examination of the ureteropelvic junction (UPJ) segments of pediatric and adult patients who had undergone AndersonHynes pyeloplasty for ureteropelvic junction obstruction (UPJO). Materials and Methods Histopathological evaluation was made of the UPJ segments of 52 patients who underwent Anderson-Hynes pyeloplasty for UPJO between January 2005 and January 2008. Patients were separated into 2 groups as pediatric, aged ≤15 years (group 1, n=10) and adult, aged >15 years (group 2, n=42). UPJ segments of both groups were compared histopathologically (collagen type 3, elastin, fibrosis and cajal cells). Radiographic evaluations were made with diuretic renogram and/or intravenous pyelography. Results Mean age of group 1 patients was 8.12±2.6 years (1-12 years) and of group 2 patients, 38.16±5.91 years (16-62 years). Mean follow-up period was 18 months (9-24 months). No statistically significant difference was determined between the groups in respect of collagen type 3, elastin, fibrosis or cajal cells (p>0.05). Conclusion As the pathology in the UPJ obstruction is a congenital defect, the histopathology does not change with age.http://jurolsurgery.org/article_7424/Changes-In-Collagen-Type-3-Elastin-Fibrosis-And-Cajal-Cell-In-Congenital-Ureteropelvic-Junction-ObstructionUreteropelvic junction obstructionhistopathologypediatricadult |
| spellingShingle | Hasan Deliktaş Oktay Issı Abdullah Gedik Hayrettin Şahin Changes in Collagen Type 3, Elastin, Fibrosis and Cajal Cell in Congenital Ureteropelvic Junction Obstruction Journal of Urological Surgery Ureteropelvic junction obstruction histopathology pediatric adult |
| title | Changes in Collagen Type 3, Elastin, Fibrosis and Cajal Cell in Congenital Ureteropelvic Junction Obstruction |
| title_full | Changes in Collagen Type 3, Elastin, Fibrosis and Cajal Cell in Congenital Ureteropelvic Junction Obstruction |
| title_fullStr | Changes in Collagen Type 3, Elastin, Fibrosis and Cajal Cell in Congenital Ureteropelvic Junction Obstruction |
| title_full_unstemmed | Changes in Collagen Type 3, Elastin, Fibrosis and Cajal Cell in Congenital Ureteropelvic Junction Obstruction |
| title_short | Changes in Collagen Type 3, Elastin, Fibrosis and Cajal Cell in Congenital Ureteropelvic Junction Obstruction |
| title_sort | changes in collagen type 3 elastin fibrosis and cajal cell in congenital ureteropelvic junction obstruction |
| topic | Ureteropelvic junction obstruction histopathology pediatric adult |
| url | http://jurolsurgery.org/article_7424/Changes-In-Collagen-Type-3-Elastin-Fibrosis-And-Cajal-Cell-In-Congenital-Ureteropelvic-Junction-Obstruction |
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