Exosomes from Ureaplasma parvum-infected ectocervical epithelial cells promote feto-maternal interface inflammation but are insufficient to cause preterm delivery

Exosomes from Ureaplasma parvum-infected ectocervical epithelial cells promote feto-maternal interface inflammation but are insufficient to cause preterm delivery

This study determined if exosomes from ectocervical epithelial (ECTO) cells infected with Ureaplasma parvum (U. parvum) can carry bacterial antigens and cause inflammation at the feto-maternal interface using two organ-on-chip devices, one representing the vagina-cervix-decidua and another one mimic...

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Bibliographic Details
Main Authors: Ourlad Alzeus G. Tantengco, Lauren S. Richardson, Enkhtuya Radnaa, Ananth Kumar Kammala, Sungjin Kim, Paul Mark B. Medina, Arum Han, Ramkumar Menon
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
extracellular vesicles
organ-on-a-chip
cervix
fetal membrane
genital mycoplasma
pregnancy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.931609/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.931609/full

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