Macrophage-derived exosomal HMGB3 regulates silica-induced pulmonary inflammation by promoting M1 macrophage polarization and recruitment

Abstract Background Chronic inflammation and fibrosis are characteristics of silicosis, and the inflammatory mediators involved in silicosis have not been fully elucidated. Recently, macrophage-derived exosomes have been reported to be inflammatory modulators, but their role in silicosis has not bee...

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Bibliographic Details
Main Authors: Xiaofeng Qin, Zhiyuan Niu, Hui Chen, Yongbin Hu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Particle and Fibre Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s12989-024-00568-8