Autosomal Dominant Polycystic Kidney Disease: Review and Management Update
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited nephropathy. Initially, it is characterised by the growth of renal cysts. Later, progressive deterioration of renal function determines the prognosis of ADPKD, depending on the main factors of progression (genetic, ren...
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| Format: | Article |
| Language: | English |
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European Medical Journal
2014-07-01
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| Series: | European Medical Journal Nephrology |
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| Online Access: | http://emjreviews.com/wp-content/uploads/Autosomal-Dominant-Polycystic-Kidney-Disease-Review-And-Management-Update.pdf |
| _version_ | 1818020237643087872 |
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| author | Víctor Martínez |
| author_facet | Víctor Martínez |
| author_sort | Víctor Martínez |
| collection | DOAJ |
| description | Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited nephropathy. Initially, it is characterised by the growth of renal cysts. Later, progressive deterioration of renal function determines the prognosis of ADPKD, depending on the main factors of progression (genetic, renal volume, and hypertension). Ultrasonography is the diagnostic technique of choice in the screening for relatives of ADPKD patients. Due to the absence of specific treatment it is necessary, in many cases, to start with renal replacement therapy. ADPKD can also be associated with extrarenal manifestations, mainly polycystic liver disease and cerebral aneurysms, which contribute to increased morbidity and mortality of these patients. |
| first_indexed | 2024-04-14T08:03:20Z |
| format | Article |
| id | doaj.art-7525529a7b404337bf51f8102474054c |
| institution | Directory Open Access Journal |
| issn | 2053-4248 2053-4248 |
| language | English |
| last_indexed | 2024-04-14T08:03:20Z |
| publishDate | 2014-07-01 |
| publisher | European Medical Journal |
| record_format | Article |
| series | European Medical Journal Nephrology |
| spelling | doaj.art-7525529a7b404337bf51f8102474054c2022-12-22T02:04:50ZengEuropean Medical JournalEuropean Medical Journal Nephrology2053-42482053-42482014-07-01216166Autosomal Dominant Polycystic Kidney Disease: Review and Management UpdateVíctor Martínez0Nephrology Department, Hospital Reína Sofía, Murcia, SpainAutosomal dominant polycystic kidney disease (ADPKD) is the most common inherited nephropathy. Initially, it is characterised by the growth of renal cysts. Later, progressive deterioration of renal function determines the prognosis of ADPKD, depending on the main factors of progression (genetic, renal volume, and hypertension). Ultrasonography is the diagnostic technique of choice in the screening for relatives of ADPKD patients. Due to the absence of specific treatment it is necessary, in many cases, to start with renal replacement therapy. ADPKD can also be associated with extrarenal manifestations, mainly polycystic liver disease and cerebral aneurysms, which contribute to increased morbidity and mortality of these patients.http://emjreviews.com/wp-content/uploads/Autosomal-Dominant-Polycystic-Kidney-Disease-Review-And-Management-Update.pdfAutosomal dominant polycystic kidney disease (ADPKD)diagnosiscysts complicationsrenal disease progressionextrarenal manifestations |
| spellingShingle | Víctor Martínez Autosomal Dominant Polycystic Kidney Disease: Review and Management Update European Medical Journal Nephrology Autosomal dominant polycystic kidney disease (ADPKD) diagnosis cysts complications renal disease progression extrarenal manifestations |
| title | Autosomal Dominant Polycystic Kidney Disease: Review and Management Update |
| title_full | Autosomal Dominant Polycystic Kidney Disease: Review and Management Update |
| title_fullStr | Autosomal Dominant Polycystic Kidney Disease: Review and Management Update |
| title_full_unstemmed | Autosomal Dominant Polycystic Kidney Disease: Review and Management Update |
| title_short | Autosomal Dominant Polycystic Kidney Disease: Review and Management Update |
| title_sort | autosomal dominant polycystic kidney disease review and management update |
| topic | Autosomal dominant polycystic kidney disease (ADPKD) diagnosis cysts complications renal disease progression extrarenal manifestations |
| url | http://emjreviews.com/wp-content/uploads/Autosomal-Dominant-Polycystic-Kidney-Disease-Review-And-Management-Update.pdf |
| work_keys_str_mv | AT victormartinez autosomaldominantpolycystickidneydiseasereviewandmanagementupdate |