Exploring the binding interactions of NOP receptor with designed natural phytochemical-neuropeptide conjugates: an in silico and SPR study

Exploring the binding interactions of NOP receptor with designed natural phytochemical-neuropeptide conjugates: an in silico and SPR study

Abstract The Nociceptin/orphanin FQ peptide (NOP) receptor is considered a member of the opioid receptor subfamily of G-protein coupled receptors (GPCRs) which has been shown to be present in many parts of the central nervous system (CNS). It plays biologically diverse roles in pain modulation, immu...

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Bibliographic Details
Main Authors: Molly E. Murray, Beatriz G. Goncalves, Mary A. Biggs, Sophia A. Frantzeskos, Charlotta G. Lebedenko, Ipsita A. Banerjee
Format: Article
Language:English
Published: SpringerOpen 2024-03-01
Series:Applied Biological Chemistry
Subjects:
Nociceptin/orphanin FQ peptide receptor (NOP) receptor
Peptide binding
Melanocyte inhibiting factor-1
Molecular dynamics
Online Access:https://doi.org/10.1186/s13765-024-00876-9

Internet

https://doi.org/10.1186/s13765-024-00876-9

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