Melatonin in treatment of climacteric symptoms
During menopausal transition women develop vasomotor and psychosomatic symptoms. These symptoms stem both from estrogen deprivation and hypothalamic-pituitary system ageing. Melatonin is a powerful hormonal adaptogen, working at every level of reproductive system, down to receptor level. To measure...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IP Berlin A.V.
2015-10-01
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| Series: | Гинекология |
| Subjects: | |
| Online Access: | https://gynecology.orscience.ru/2079-5831/article/viewFile/28481/pdf |
| _version_ | 1818210612185923584 |
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| author | I V Kuznetsova D I Burchakov |
| author_facet | I V Kuznetsova D I Burchakov |
| author_sort | I V Kuznetsova |
| collection | DOAJ |
| description | During menopausal transition women develop vasomotor and psychosomatic symptoms. These symptoms stem both from estrogen deprivation and hypothalamic-pituitary system ageing. Melatonin is a powerful hormonal adaptogen, working at every level of reproductive system, down to receptor level. To measure its effect on climacteric symptoms, we enrolled 55 women between 45 and 65 y.o. All participants took 3 mg of melatonin - Melaxen (Unipharm, Inc.) for 3 months. During the therapy we observed marked reduction of symptoms from 40.96 to 21.36 (47.92%) on Greene Climacteric Scale and sleep improvement from 16.60±4.03 to 7.33±1.95 on Pittsburgh Sleep Quality Index. Melatonin 3 mg is an effective method of climacteric symptoms therapy. |
| first_indexed | 2024-12-12T05:19:22Z |
| format | Article |
| id | doaj.art-752a5ae78e99488888419727570f65c2 |
| institution | Directory Open Access Journal |
| issn | 2079-5696 2079-5831 |
| language | Russian |
| last_indexed | 2024-12-12T05:19:22Z |
| publishDate | 2015-10-01 |
| publisher | IP Berlin A.V. |
| record_format | Article |
| series | Гинекология |
| spelling | doaj.art-752a5ae78e99488888419727570f65c22022-12-22T00:36:39ZrusIP Berlin A.V.Гинекология2079-56962079-58312015-10-01175444825611Melatonin in treatment of climacteric symptomsI V Kuznetsova0D I Burchakov1I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationEndocrinology research center of the Ministry of Health of the Russian FederationDuring menopausal transition women develop vasomotor and psychosomatic symptoms. These symptoms stem both from estrogen deprivation and hypothalamic-pituitary system ageing. Melatonin is a powerful hormonal adaptogen, working at every level of reproductive system, down to receptor level. To measure its effect on climacteric symptoms, we enrolled 55 women between 45 and 65 y.o. All participants took 3 mg of melatonin - Melaxen (Unipharm, Inc.) for 3 months. During the therapy we observed marked reduction of symptoms from 40.96 to 21.36 (47.92%) on Greene Climacteric Scale and sleep improvement from 16.60±4.03 to 7.33±1.95 on Pittsburgh Sleep Quality Index. Melatonin 3 mg is an effective method of climacteric symptoms therapy.https://gynecology.orscience.ru/2079-5831/article/viewFile/28481/pdfmenopausal symptomstreatmentmelatonin |
| spellingShingle | I V Kuznetsova D I Burchakov Melatonin in treatment of climacteric symptoms Гинекология menopausal symptoms treatment melatonin |
| title | Melatonin in treatment of climacteric symptoms |
| title_full | Melatonin in treatment of climacteric symptoms |
| title_fullStr | Melatonin in treatment of climacteric symptoms |
| title_full_unstemmed | Melatonin in treatment of climacteric symptoms |
| title_short | Melatonin in treatment of climacteric symptoms |
| title_sort | melatonin in treatment of climacteric symptoms |
| topic | menopausal symptoms treatment melatonin |
| url | https://gynecology.orscience.ru/2079-5831/article/viewFile/28481/pdf |
| work_keys_str_mv | AT ivkuznetsova melatoninintreatmentofclimactericsymptoms AT diburchakov melatoninintreatmentofclimactericsymptoms |