Identification of Age-Associated Transcriptomic Changes Linked to Immunotherapy Response in Primary Melanoma

Identification of Age-Associated Transcriptomic Changes Linked to Immunotherapy Response in Primary Melanoma

Melanoma is a lethal form of skin cancer. Immunotherapeutic agents such as anti-PD-1 (pembrolizumab and nivolumab) and anti-CTLA-4 (ipilimumab) have revolutionized melanoma treatment; however, drug resistance is rapidly acquired. Several studies have reported an increase in melanoma rates in older p...

Full description

Bibliographic Details
Main Authors: Nehal Farid El-Helbawy, Ahmed Ezat El Zowalaty
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Current Issues in Molecular Biology
Subjects:
melanoma
ageing
RNA-seq
transcriptional profiles
gene expression
immunotherapy
Online Access:https://www.mdpi.com/1467-3045/44/9/282

Similar Items

Similar Items