Systematic review of diagnostic and prognostic host blood transcriptomic signatures of tuberculosis disease in people living with HIV [version 2; peer review: 2 approved]

Systematic review of diagnostic and prognostic host blood transcriptomic signatures of tuberculosis disease in people living with HIV [version 2; peer review: 2 approved]

Background HIV-associated tuberculosis (TB) has high mortality; however, current triage and prognostic tools offer poor sensitivity and specificity, respectively. We conducted a systematic review of diagnostic and prognostic host-blood transcriptomic signatures of TB in people living with HIV (PLHIV...

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Bibliographic Details
Main Authors: Simon C Mendelsohn, Humphrey Mulenga, Savannah Verhage, Thomas J Scriba, Mark Hatherill
Format: Article
Language:English
Published: F1000 Research Ltd 2023-05-01
Series:Gates Open Research
Subjects:
Host
blood
diagnostic
prognostic
gene
signatures
eng
Online Access:https://gatesopenresearch.org/articles/7-27/v2

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