Nanomaterials Aiming to Tackle Antibiotic-Resistant Bacteria

The global health of humans is seriously affected by the dramatic increases in the resistance patterns of antimicrobials against virulent bacteria. From the statements released by the Centers for Disease Control and Prevention about the world entering a post-antibiotic era, and forecasts about human...

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Main Authors: Muhammad Usman Munir, Muhammad Masood Ahmad
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/14/3/582
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author Muhammad Usman Munir
Muhammad Masood Ahmad
author_facet Muhammad Usman Munir
Muhammad Masood Ahmad
author_sort Muhammad Usman Munir
collection DOAJ
description The global health of humans is seriously affected by the dramatic increases in the resistance patterns of antimicrobials against virulent bacteria. From the statements released by the Centers for Disease Control and Prevention about the world entering a post-antibiotic era, and forecasts about human mortality due to bacterial infection being increased compared to cancer, the current body of literature indicates that emerging tools such as nanoparticles can be used against lethal infections caused by bacteria. Furthermore, a different concept of nanomaterial-based methods can cope with the hindrance faced by common antimicrobials, such as resistance to antibiotics. The current review focuses on different approaches to inhibiting bacterial infection using nanoparticles and aiding in the fabrication of antimicrobial nanotherapeutics by emphasizing the functionality of nanomaterial surface design and fabrication for antimicrobial cargo.
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spelling doaj.art-7530f7596cab4c8190b31cb24ea3de5b2023-11-30T21:56:58ZengMDPI AGPharmaceutics1999-49232022-03-0114358210.3390/pharmaceutics14030582Nanomaterials Aiming to Tackle Antibiotic-Resistant BacteriaMuhammad Usman Munir0Muhammad Masood Ahmad1Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka 72388, Aljouf, Saudi ArabiaDepartment of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka 72388, Aljouf, Saudi ArabiaThe global health of humans is seriously affected by the dramatic increases in the resistance patterns of antimicrobials against virulent bacteria. From the statements released by the Centers for Disease Control and Prevention about the world entering a post-antibiotic era, and forecasts about human mortality due to bacterial infection being increased compared to cancer, the current body of literature indicates that emerging tools such as nanoparticles can be used against lethal infections caused by bacteria. Furthermore, a different concept of nanomaterial-based methods can cope with the hindrance faced by common antimicrobials, such as resistance to antibiotics. The current review focuses on different approaches to inhibiting bacterial infection using nanoparticles and aiding in the fabrication of antimicrobial nanotherapeutics by emphasizing the functionality of nanomaterial surface design and fabrication for antimicrobial cargo.https://www.mdpi.com/1999-4923/14/3/582antimicrobial nanomaterialantibiotic resistancemetallic nanoparticlebacterial biofilmmultidrug-resistant bacteria
spellingShingle Muhammad Usman Munir
Muhammad Masood Ahmad
Nanomaterials Aiming to Tackle Antibiotic-Resistant Bacteria
Pharmaceutics
antimicrobial nanomaterial
antibiotic resistance
metallic nanoparticle
bacterial biofilm
multidrug-resistant bacteria
title Nanomaterials Aiming to Tackle Antibiotic-Resistant Bacteria
title_full Nanomaterials Aiming to Tackle Antibiotic-Resistant Bacteria
title_fullStr Nanomaterials Aiming to Tackle Antibiotic-Resistant Bacteria
title_full_unstemmed Nanomaterials Aiming to Tackle Antibiotic-Resistant Bacteria
title_short Nanomaterials Aiming to Tackle Antibiotic-Resistant Bacteria
title_sort nanomaterials aiming to tackle antibiotic resistant bacteria
topic antimicrobial nanomaterial
antibiotic resistance
metallic nanoparticle
bacterial biofilm
multidrug-resistant bacteria
url https://www.mdpi.com/1999-4923/14/3/582
work_keys_str_mv AT muhammadusmanmunir nanomaterialsaimingtotackleantibioticresistantbacteria
AT muhammadmasoodahmad nanomaterialsaimingtotackleantibioticresistantbacteria