Management of convulsive status epilepticus: recent updates
Convulsive status epilepticus (SE) is a medical emergency associated with high morbidity and mortality. Recently, clinical trials and meta-analyses investigating medical treatment of SE have been published. Benzodiazepine is well known as the first-line treatment for SE. Recent evidence suggests the...
| Main Author: | |
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| Format: | Article |
| Language: | English |
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Korean Encephalitis and Neuroinflammation Society
2023-04-01
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| Series: | Encephalitis |
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| Online Access: | http://www.encephalitisjournal.org/upload/pdf/encephalitis-2022-00087.pdf |
| _version_ | 1797838513111040000 |
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| author | Jung-Ick Byun |
| author_facet | Jung-Ick Byun |
| author_sort | Jung-Ick Byun |
| collection | DOAJ |
| description | Convulsive status epilepticus (SE) is a medical emergency associated with high morbidity and mortality. Recently, clinical trials and meta-analyses investigating medical treatment of SE have been published. Benzodiazepine is well known as the first-line treatment for SE. Recent evidence suggests the equivalence of intravenous fosphenytoin, valproate, and levetiracetam for treatment of established SE. There is lack of evidence regarding treatment for refractory SE. Intravenous midazolam is commonly used, and recent evidence supports the use of ketamine. Additional studies are needed to improve the management of convulsive SE. |
| first_indexed | 2024-04-09T15:42:04Z |
| format | Article |
| id | doaj.art-753255b0f1a1477da270428023f8c6f7 |
| institution | Directory Open Access Journal |
| issn | 2765-4559 2734-1461 |
| language | English |
| last_indexed | 2024-04-09T15:42:04Z |
| publishDate | 2023-04-01 |
| publisher | Korean Encephalitis and Neuroinflammation Society |
| record_format | Article |
| series | Encephalitis |
| spelling | doaj.art-753255b0f1a1477da270428023f8c6f72023-04-27T06:41:47ZengKorean Encephalitis and Neuroinflammation SocietyEncephalitis2765-45592734-14612023-04-0132394310.47936/encephalitis.2022.0008745Management of convulsive status epilepticus: recent updatesJung-Ick ByunConvulsive status epilepticus (SE) is a medical emergency associated with high morbidity and mortality. Recently, clinical trials and meta-analyses investigating medical treatment of SE have been published. Benzodiazepine is well known as the first-line treatment for SE. Recent evidence suggests the equivalence of intravenous fosphenytoin, valproate, and levetiracetam for treatment of established SE. There is lack of evidence regarding treatment for refractory SE. Intravenous midazolam is commonly used, and recent evidence supports the use of ketamine. Additional studies are needed to improve the management of convulsive SE.http://www.encephalitisjournal.org/upload/pdf/encephalitis-2022-00087.pdfstatus epilepticusrandomized controlled trialdrug therapy |
| spellingShingle | Jung-Ick Byun Management of convulsive status epilepticus: recent updates Encephalitis status epilepticus randomized controlled trial drug therapy |
| title | Management of convulsive status epilepticus: recent updates |
| title_full | Management of convulsive status epilepticus: recent updates |
| title_fullStr | Management of convulsive status epilepticus: recent updates |
| title_full_unstemmed | Management of convulsive status epilepticus: recent updates |
| title_short | Management of convulsive status epilepticus: recent updates |
| title_sort | management of convulsive status epilepticus recent updates |
| topic | status epilepticus randomized controlled trial drug therapy |
| url | http://www.encephalitisjournal.org/upload/pdf/encephalitis-2022-00087.pdf |
| work_keys_str_mv | AT jungickbyun managementofconvulsivestatusepilepticusrecentupdates |