G Protein-Coupled Estrogen Receptor in Cancer and Stromal Cells: Functions and Novel Therapeutic Perspectives

G Protein-Coupled Estrogen Receptor in Cancer and Stromal Cells: Functions and Novel Therapeutic Perspectives

Estrogen is involved in numerous physiological and pathophysiological systems. Its role in driving estrogen receptor-expressing breast cancers is well established, but it also has important roles in a number of other cancers, acting both on tumor cells directly as well as in the function of multiple...

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Bibliographic Details
Main Authors: Richard A. Pepermans, Geetanjali Sharma, Eric R. Prossnitz
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
estrogen
GPER
cancer
stroma
metabolism
obesity
Online Access:https://www.mdpi.com/2073-4409/10/3/672

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