Application of Homology Modeling by Enhanced Profile–Profile Alignment and Flexible-Fitting Simulation to Cryo-EM Based Structure Determination

Application of cryo-electron microscopy (cryo-EM) is crucially important for ascertaining the atomic structure of large biomolecules such as ribosomes and protein complexes in membranes. Advances in cryo-EM technology and software have made it possible to obtain data with near-atomic resolution, but...

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Bibliographic Details
Main Authors:	Yu Yamamori, Kentaro Tomii
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	International Journal of Molecular Sciences
Subjects:	cryo-EM flexible fitting homology modeling profile–profile alignment
Online Access:	https://www.mdpi.com/1422-0067/23/4/1977

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