Altered gut mycobiome in patients with end-stage renal disease and its correlations with serum and fecal metabolomes

Altered gut mycobiome in patients with end-stage renal disease and its correlations with serum and fecal metabolomes

Abstract Background The relationship between the gut mycobiome and end-stage renal disease (ESRD) remains largely unexplored. Methods In this study, we compared the gut fungal populations of 223 ESRD patients and 69 healthy controls (HCs) based on shotgun metagenomic sequencing data, and analyzed th...

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Bibliographic Details
Main Authors: Yi Ren, Lei Chen, Ruochun Guo, Shiyang Ma, Shenghui Li, Yue Zhang, Hongli Jiang, Haitao Shi, Pan Zhang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Translational Medicine
Subjects:
End-stage renal disease
Gut mycobiome
Shotgun metagenome sequencing
Serum metabolome
Fecal metabolome
Online Access:https://doi.org/10.1186/s12967-024-05004-1

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