Madagascine induces vasodilatation via activation of AMPK

Madagascine induces vasodilatation via activation of AMPK

Madagascine (3-isopentenyloxyemodin) can be chemically synthesized or purified from several Rhamnus species, and it is found to have more potent biological activities than the parent compound emodin. The aim of this study is to characterize the vasodilatory effect of madagascine on vasoconstriction...

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Bibliographic Details
Main Authors: Dapeng Chen, Bochao Lv, Sei Kobayashi, Yongjian Xiong, Yuan Lin, Salvatore Genovese, Francesco Epifano, Shanshan Hou, Yunyan Ji, Fusheng Tang, Dandan Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Pharmacology
Subjects:
Vasoconstriction
AMPK
eNOS
vasospasm
Madagascine
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00435/full

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