Hepatoprotective properties of water kefir: A traditional fermented drink and its potential role

The liver is extremely vulnerable to damage because of its role in metabolism. Toxin, metabolic syndrome, alcohol, microorganisms, and autoimmune diseases can be the cause of liver damage. While different etiologies can cause liver disease, pathophysiologically, there are similarities in the role of...

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Main Authors: Widhya Aligita, Marlia Singgih, Entris Sutrisno, I K Adnyana
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:International Journal of Preventive Medicine
Subjects:
Online Access:http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2023;volume=14;issue=1;spage=93;epage=93;aulast=Aligita
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author Widhya Aligita
Marlia Singgih
Entris Sutrisno
I K Adnyana
author_facet Widhya Aligita
Marlia Singgih
Entris Sutrisno
I K Adnyana
author_sort Widhya Aligita
collection DOAJ
description The liver is extremely vulnerable to damage because of its role in metabolism. Toxin, metabolic syndrome, alcohol, microorganisms, and autoimmune diseases can be the cause of liver damage. While different etiologies can cause liver disease, pathophysiologically, there are similarities in the role of free radicals, inflammatory mediators, and gut microbiome during the disease development. Therefore, ingredients with antioxidant, antiinflammatory, and antidysbiotic properties have the potential to act as hepatoprotectors; and water kefir is one of them. Water kefir is a traditional fermented drink made from water kefir grains, sugar, and dried fruit. Water kefir is dominated by lactic acid bacteria and yeast as a fermented beverage, and several species of this group of microorganisms have been shown as probiotics. According to researches, water kefir has strong antioxidant, antiinflammatory, and hepatoprotective effects. Even so, there are still few researches reported about water kefir as a hepatoprotective agent. Several studies, on the other hand, showed promising results. This review discusses the relationship between the pathophysiology of liver disease and the pharmacological activity of water kefir and other probiotics in general, which leads to the potential prospect of water kefir research as a hepatoprotective agent.
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spelling doaj.art-7538880f2c154a70a4fedb2ce653daa92023-08-23T08:52:52ZengWolters Kluwer Medknow PublicationsInternational Journal of Preventive Medicine2008-78022008-82132023-01-01141939310.4103/ijpvm.ijpvm_29_22Hepatoprotective properties of water kefir: A traditional fermented drink and its potential roleWidhya AligitaMarlia SinggihEntris SutrisnoI K AdnyanaThe liver is extremely vulnerable to damage because of its role in metabolism. Toxin, metabolic syndrome, alcohol, microorganisms, and autoimmune diseases can be the cause of liver damage. While different etiologies can cause liver disease, pathophysiologically, there are similarities in the role of free radicals, inflammatory mediators, and gut microbiome during the disease development. Therefore, ingredients with antioxidant, antiinflammatory, and antidysbiotic properties have the potential to act as hepatoprotectors; and water kefir is one of them. Water kefir is a traditional fermented drink made from water kefir grains, sugar, and dried fruit. Water kefir is dominated by lactic acid bacteria and yeast as a fermented beverage, and several species of this group of microorganisms have been shown as probiotics. According to researches, water kefir has strong antioxidant, antiinflammatory, and hepatoprotective effects. Even so, there are still few researches reported about water kefir as a hepatoprotective agent. Several studies, on the other hand, showed promising results. This review discusses the relationship between the pathophysiology of liver disease and the pharmacological activity of water kefir and other probiotics in general, which leads to the potential prospect of water kefir research as a hepatoprotective agent.http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2023;volume=14;issue=1;spage=93;epage=93;aulast=Aligitaantioxidanthepatoprotectorinflammationprobioticwater kefir
spellingShingle Widhya Aligita
Marlia Singgih
Entris Sutrisno
I K Adnyana
Hepatoprotective properties of water kefir: A traditional fermented drink and its potential role
International Journal of Preventive Medicine
antioxidant
hepatoprotector
inflammation
probiotic
water kefir
title Hepatoprotective properties of water kefir: A traditional fermented drink and its potential role
title_full Hepatoprotective properties of water kefir: A traditional fermented drink and its potential role
title_fullStr Hepatoprotective properties of water kefir: A traditional fermented drink and its potential role
title_full_unstemmed Hepatoprotective properties of water kefir: A traditional fermented drink and its potential role
title_short Hepatoprotective properties of water kefir: A traditional fermented drink and its potential role
title_sort hepatoprotective properties of water kefir a traditional fermented drink and its potential role
topic antioxidant
hepatoprotector
inflammation
probiotic
water kefir
url http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2023;volume=14;issue=1;spage=93;epage=93;aulast=Aligita
work_keys_str_mv AT widhyaaligita hepatoprotectivepropertiesofwaterkefiratraditionalfermenteddrinkanditspotentialrole
AT marliasinggih hepatoprotectivepropertiesofwaterkefiratraditionalfermenteddrinkanditspotentialrole
AT entrissutrisno hepatoprotectivepropertiesofwaterkefiratraditionalfermenteddrinkanditspotentialrole
AT ikadnyana hepatoprotectivepropertiesofwaterkefiratraditionalfermenteddrinkanditspotentialrole