Characterization of the Sphingolipidome of the Peri-Infarct Tissue during Hemorrhagic Transformation in a Mouse Model of Cerebral Ischemia

Characterization of the Sphingolipidome of the Peri-Infarct Tissue during Hemorrhagic Transformation in a Mouse Model of Cerebral Ischemia

Background: Cardiovascular diseases like stroke cause changes to sphingolipid mediators like sphingosine 1-phosphate (S1P) or its ceramide analogs, which bear the potential to either alleviate or exacerbate the neurological damage. Therefore, the precise identification of alterations within the sphi...

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Bibliographic Details
Main Authors: Alexandra Lucaciu, Sandra Trautmann, Dominique Thomas, Karsten Lachner, Robert Brunkhorst, Julien Subburayalu
Format: Article
Language:English
Published: IMR Press 2022-09-01
Series:Journal of Integrative Neuroscience
Subjects:
sphingosine 1-phosphate
ceramide
s1p 1
ischemic stroke
hemorrhagic transformation
sphingolipid profiling
mcao
c57bl/6
Online Access:https://www.imrpress.com/journal/JIN/21/6/10.31083/j.jin2106161

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