Insomnia partially mediates the relationship between pathological personality traits and depression: a case-control study
Background and Objective Personality disorders are frequently associated with insomnia and depression, but little is known about the inter-relationships among these variables. Therefore, this study examined these inter-relationships and the possible mediating effect of insomnia on the association be...
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PeerJ Inc.
2021-03-01
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| Online Access: | https://peerj.com/articles/11061.pdf |
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| author | Fenglan Chen Xiujin Lin Yuli Pan Xuan Zeng Shengjie Zhang Hong Hu Miaoyu Yu Junduan Wu |
| author_facet | Fenglan Chen Xiujin Lin Yuli Pan Xuan Zeng Shengjie Zhang Hong Hu Miaoyu Yu Junduan Wu |
| author_sort | Fenglan Chen |
| collection | DOAJ |
| description | Background and Objective Personality disorders are frequently associated with insomnia and depression, but little is known about the inter-relationships among these variables. Therefore, this study examined these inter-relationships and the possible mediating effect of insomnia on the association between specific personality pathologies and depression severity. Methods There were 138 study participants, including 69 individuals with depression and 69 healthy controls. The main variables were measured by the Hamilton Depression Rating Scale-24 (HAMD-24), Athens Sleep Insomnia Scale (AIS), and the Personality Diagnostic Questionnaire (PDQ-4+). Multivariate linear regression and mediation analysis were conducted. Results With the exception of the antisocial personality score, all the PDQ-4+ scores and AIS scores were significantly higher in the depression group than in the healthy control group (p < 0.001). In the total sample, all personality pathology scores (p < 0.001), except the antisocial personality score, had significant positive correlations with the AIS scores and HAMD-24 scores, and the AIS scores and HAMD-24 scores were positively correlated (r = 0.620, p < 0.001). Regression analysis revealed that borderline personality, passive-aggressive personality, and insomnia positively predicted the severity of depression, after adjusting for sociodemographic covariates, and that insomnia partially mediated the associations of borderline personality and passive-aggressive personality with depression severity. Conclusions Borderline personality, passive-aggressive personality, and insomnia tend to increase the severity of depression, and the effect of borderline and passive-aggressive personality on depression severity may be partially mediated by insomnia. This is the first study to report these findings in a Chinese sample, and they may help researchers to understand the pathways from specific personality pathologies to the psychopathology of depression better, which should be useful for designing interventions to relieve depression severity, as the impact of specific personality pathology and insomnia should be considered. |
| first_indexed | 2024-03-09T06:46:22Z |
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| language | English |
| last_indexed | 2024-03-09T06:46:22Z |
| publishDate | 2021-03-01 |
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| spelling | doaj.art-753c34515a7249709bf4ee7660569d7c2023-12-03T10:35:50ZengPeerJ Inc.PeerJ2167-83592021-03-019e1106110.7717/peerj.11061Insomnia partially mediates the relationship between pathological personality traits and depression: a case-control studyFenglan Chen0Xiujin Lin1Yuli Pan2Xuan Zeng3Shengjie Zhang4Hong Hu5Miaoyu Yu6Junduan Wu7Department of Psychology, School of Public Health, Guangxi Medical University, Nanning, Guangxi, ChinaDepartment of Maternal and Child Health, School of Public Health, Sun Yat-Sen University, Guangzhou, Guangdong, ChinaDepartment of Psychology, School of Public Health, Guangxi Medical University, Nanning, Guangxi, ChinaDepartment of Child Healthcare, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou, Guangxi, ChinaDepartment of Psychology, School of Public Health, Guangxi Medical University, Nanning, Guangxi, ChinaDepartment of Psychology, School of Public Health, Guangxi Medical University, Nanning, Guangxi, ChinaDepartment of Mental Health, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, ChinaDepartment of Psychology, School of Public Health, Guangxi Medical University, Nanning, Guangxi, ChinaBackground and Objective Personality disorders are frequently associated with insomnia and depression, but little is known about the inter-relationships among these variables. Therefore, this study examined these inter-relationships and the possible mediating effect of insomnia on the association between specific personality pathologies and depression severity. Methods There were 138 study participants, including 69 individuals with depression and 69 healthy controls. The main variables were measured by the Hamilton Depression Rating Scale-24 (HAMD-24), Athens Sleep Insomnia Scale (AIS), and the Personality Diagnostic Questionnaire (PDQ-4+). Multivariate linear regression and mediation analysis were conducted. Results With the exception of the antisocial personality score, all the PDQ-4+ scores and AIS scores were significantly higher in the depression group than in the healthy control group (p < 0.001). In the total sample, all personality pathology scores (p < 0.001), except the antisocial personality score, had significant positive correlations with the AIS scores and HAMD-24 scores, and the AIS scores and HAMD-24 scores were positively correlated (r = 0.620, p < 0.001). Regression analysis revealed that borderline personality, passive-aggressive personality, and insomnia positively predicted the severity of depression, after adjusting for sociodemographic covariates, and that insomnia partially mediated the associations of borderline personality and passive-aggressive personality with depression severity. Conclusions Borderline personality, passive-aggressive personality, and insomnia tend to increase the severity of depression, and the effect of borderline and passive-aggressive personality on depression severity may be partially mediated by insomnia. This is the first study to report these findings in a Chinese sample, and they may help researchers to understand the pathways from specific personality pathologies to the psychopathology of depression better, which should be useful for designing interventions to relieve depression severity, as the impact of specific personality pathology and insomnia should be considered.https://peerj.com/articles/11061.pdfPersonality pathologyInsomniaDepressionMediation |
| spellingShingle | Fenglan Chen Xiujin Lin Yuli Pan Xuan Zeng Shengjie Zhang Hong Hu Miaoyu Yu Junduan Wu Insomnia partially mediates the relationship between pathological personality traits and depression: a case-control study PeerJ Personality pathology Insomnia Depression Mediation |
| title | Insomnia partially mediates the relationship between pathological personality traits and depression: a case-control study |
| title_full | Insomnia partially mediates the relationship between pathological personality traits and depression: a case-control study |
| title_fullStr | Insomnia partially mediates the relationship between pathological personality traits and depression: a case-control study |
| title_full_unstemmed | Insomnia partially mediates the relationship between pathological personality traits and depression: a case-control study |
| title_short | Insomnia partially mediates the relationship between pathological personality traits and depression: a case-control study |
| title_sort | insomnia partially mediates the relationship between pathological personality traits and depression a case control study |
| topic | Personality pathology Insomnia Depression Mediation |
| url | https://peerj.com/articles/11061.pdf |
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