Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes
Fibroblastic reticular cells (FRC) form the structural backbone of the T cell rich zones in secondary lymphoid organs, but also actively influence the adaptive immune response. They provide a guidance path for immigrating T lymphocytes and dendritic cells (DC) and are the main local source of the cy...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-09-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00285/full |