Bicarbonate Increases Ischemia-Reperfusion Damage by Inhibiting Mitophagy.

During an ischemic event, bicarbonate and CO2 concentration increase as a consequence of O2 consumption and lack of blood flow. This event is important as bicarbonate/CO2 is determinant for several redox and enzymatic reactions, in addition to pH regulation. Until now, most work done on the role of...

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Bibliographic Details
Main Authors: Bruno B Queliconi, Alicia J Kowaltowski, Roberta A Gottlieb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5156406?pdf=render

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