Bicarbonate Increases Ischemia-Reperfusion Damage by Inhibiting Mitophagy.
During an ischemic event, bicarbonate and CO2 concentration increase as a consequence of O2 consumption and lack of blood flow. This event is important as bicarbonate/CO2 is determinant for several redox and enzymatic reactions, in addition to pH regulation. Until now, most work done on the role of...
Main Authors: | Bruno B Queliconi, Alicia J Kowaltowski, Roberta A Gottlieb |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5156406?pdf=render |
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