Merging into the mainstream: the evolution of the role of point-of-care musculoskeletal ultrasound in hemophilia [version 1; peer review: 2 approved]
Bleeding with resultant hemophilic arthropathy constitutes the largest cause of morbidity in patients with hemophilia. It results from repeated bleeding episodes in the joint and is characterized by synovial hypertrophy and cartilage and bony destruction. Hemophilic arthropathy assessment is a conti...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2019-07-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/8-1029/v1 |
| _version_ | 1818872971212619776 |
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| author | Nihal Bakeer Amy D Shapiro |
| author_facet | Nihal Bakeer Amy D Shapiro |
| author_sort | Nihal Bakeer |
| collection | DOAJ |
| description | Bleeding with resultant hemophilic arthropathy constitutes the largest cause of morbidity in patients with hemophilia. It results from repeated bleeding episodes in the joint and is characterized by synovial hypertrophy and cartilage and bony destruction. Hemophilic arthropathy assessment is a continually evolving process and is particularly challenging in children and young adults in whom joint disease may be missed or underestimated as obtaining serial “baseline” magnetic resonance imaging scans of multiple clinically asymptomatic or nearly asymptomatic joints may be unjustifiable and cost-ineffective. Musculoskeletal ultrasound—particularly, point-of-care musculoskeletal ultrasound—has emerged as a promising imaging modality for the early detection and management of hemophilic arthropathy, and for the evaluation of hemarthrosis and painful musculoskeletal episodes in patients with hemophilia. This review summarizes currently available data on the emerging role of this new imaging modality, its limitations, and gaps in knowledge. The review also raises unanswered questions, highlights the need for consolidated research efforts, and delineates future directions expected to advance this technology and optimize its use in this patient population. |
| first_indexed | 2024-12-19T12:47:17Z |
| format | Article |
| id | doaj.art-7540a3e5f2a946ea9be77f91ca50de09 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-12-19T12:47:17Z |
| publishDate | 2019-07-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-7540a3e5f2a946ea9be77f91ca50de092022-12-21T20:20:42ZengF1000 Research LtdF1000Research2046-14022019-07-01810.12688/f1000research.16039.117516Merging into the mainstream: the evolution of the role of point-of-care musculoskeletal ultrasound in hemophilia [version 1; peer review: 2 approved]Nihal Bakeer0Amy D Shapiro1Indiana Hemophilia and Thrombosis Center, 8326 Naab Road, Indianapolis, IN, 46260, USAIndiana Hemophilia and Thrombosis Center, 8326 Naab Road, Indianapolis, IN, 46260, USABleeding with resultant hemophilic arthropathy constitutes the largest cause of morbidity in patients with hemophilia. It results from repeated bleeding episodes in the joint and is characterized by synovial hypertrophy and cartilage and bony destruction. Hemophilic arthropathy assessment is a continually evolving process and is particularly challenging in children and young adults in whom joint disease may be missed or underestimated as obtaining serial “baseline” magnetic resonance imaging scans of multiple clinically asymptomatic or nearly asymptomatic joints may be unjustifiable and cost-ineffective. Musculoskeletal ultrasound—particularly, point-of-care musculoskeletal ultrasound—has emerged as a promising imaging modality for the early detection and management of hemophilic arthropathy, and for the evaluation of hemarthrosis and painful musculoskeletal episodes in patients with hemophilia. This review summarizes currently available data on the emerging role of this new imaging modality, its limitations, and gaps in knowledge. The review also raises unanswered questions, highlights the need for consolidated research efforts, and delineates future directions expected to advance this technology and optimize its use in this patient population.https://f1000research.com/articles/8-1029/v1 |
| spellingShingle | Nihal Bakeer Amy D Shapiro Merging into the mainstream: the evolution of the role of point-of-care musculoskeletal ultrasound in hemophilia [version 1; peer review: 2 approved] F1000Research |
| title | Merging into the mainstream: the evolution of the role of point-of-care musculoskeletal ultrasound in hemophilia [version 1; peer review: 2 approved] |
| title_full | Merging into the mainstream: the evolution of the role of point-of-care musculoskeletal ultrasound in hemophilia [version 1; peer review: 2 approved] |
| title_fullStr | Merging into the mainstream: the evolution of the role of point-of-care musculoskeletal ultrasound in hemophilia [version 1; peer review: 2 approved] |
| title_full_unstemmed | Merging into the mainstream: the evolution of the role of point-of-care musculoskeletal ultrasound in hemophilia [version 1; peer review: 2 approved] |
| title_short | Merging into the mainstream: the evolution of the role of point-of-care musculoskeletal ultrasound in hemophilia [version 1; peer review: 2 approved] |
| title_sort | merging into the mainstream the evolution of the role of point of care musculoskeletal ultrasound in hemophilia version 1 peer review 2 approved |
| url | https://f1000research.com/articles/8-1029/v1 |
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