Congenital Zika Infection and the Risk of Neurodevelopmental, Neurological, and Urinary Track Disorders in Early Childhood. A Systematic Review
It was late 2015 when Northeast Brazil noticed a worrying increase in neonates born with microcephaly and other congenital malformations. These abnormalities, characterized by an abnormally small head and often neurological impairment and later termed Congenital Zika Syndrome, describe the severity...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/13/8/1671 |
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| author | Evangelia Antoniou Eirini Orovou Paraskevi Eva Andronikidi Christos Orovas Nikolaos Rigas Ermioni Palaska Angeliki Sarella Georgios Iatrakis Chrysa Voyiatzaki |
| author_facet | Evangelia Antoniou Eirini Orovou Paraskevi Eva Andronikidi Christos Orovas Nikolaos Rigas Ermioni Palaska Angeliki Sarella Georgios Iatrakis Chrysa Voyiatzaki |
| author_sort | Evangelia Antoniou |
| collection | DOAJ |
| description | It was late 2015 when Northeast Brazil noticed a worrying increase in neonates born with microcephaly and other congenital malformations. These abnormalities, characterized by an abnormally small head and often neurological impairment and later termed Congenital Zika Syndrome, describe the severity of neurodevelopmental and nephrological outcomes in early childhood, and the implication of microcephaly at birth. The purpose of the study was to describe the neurodevelopmental outcomes in children exposed to Zika virus during fetal life, with and without microcephaly at birth. The systematic review included research studies about the neurodevelopmental outcomes with and without microcephaly, as well as nephrological outcomes in early childhood. We searched PubMed, Crossref, PsycINFO, Scopus, and Google Scholar publications and selected 19 research articles published from 2018 to 2021. Most studies have linked the severity of microcephaly in childbirth to the neurodevelopmental and urinary outcomes in early childhood. However, most children without microcephaly at birth develop typically, while others may be at risk for language impairment. |
| first_indexed | 2024-03-10T08:17:37Z |
| format | Article |
| id | doaj.art-7541430070ad4de18aa1dcd9cd68f982 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T08:17:37Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-7541430070ad4de18aa1dcd9cd68f9822023-11-22T10:13:06ZengMDPI AGViruses1999-49152021-08-01138167110.3390/v13081671Congenital Zika Infection and the Risk of Neurodevelopmental, Neurological, and Urinary Track Disorders in Early Childhood. A Systematic ReviewEvangelia Antoniou0Eirini Orovou1Paraskevi Eva Andronikidi2Christos Orovas3Nikolaos Rigas4Ermioni Palaska5Angeliki Sarella6Georgios Iatrakis7Chrysa Voyiatzaki8Department of Midwifery, Egaleo Park Campus, University of West Attica, Ag. Spyridonos Str., 12243 Egaleo, GreeceDepartment of Midwifery, Egaleo Park Campus, University of West Attica, Ag. Spyridonos Str., 12243 Egaleo, GreeceEvaggelismos General Hospital of Athens, Ypsilandou 45-47, 10576 Athens, GreeceDepartment of Products and Systems Design Engineering, University of Western Macedonia, 50100 Kozani, GreeceDepartment of Midwifery, Egaleo Park Campus, University of West Attica, Ag. Spyridonos Str., 12243 Egaleo, GreeceDepartment of Midwifery, Egaleo Park Campus, University of West Attica, Ag. Spyridonos Str., 12243 Egaleo, GreeceDepartment of Midwifery, Egaleo Park Campus, University of West Attica, Ag. Spyridonos Str., 12243 Egaleo, GreeceDepartment of Midwifery, Egaleo Park Campus, University of West Attica, Ag. Spyridonos Str., 12243 Egaleo, GreeceDepartment of Biomedical Sciences, Egaleo Park Campus, University of West Attica, Ag. Spyridonos Str., 12243 Egaleo, GreeceIt was late 2015 when Northeast Brazil noticed a worrying increase in neonates born with microcephaly and other congenital malformations. These abnormalities, characterized by an abnormally small head and often neurological impairment and later termed Congenital Zika Syndrome, describe the severity of neurodevelopmental and nephrological outcomes in early childhood, and the implication of microcephaly at birth. The purpose of the study was to describe the neurodevelopmental outcomes in children exposed to Zika virus during fetal life, with and without microcephaly at birth. The systematic review included research studies about the neurodevelopmental outcomes with and without microcephaly, as well as nephrological outcomes in early childhood. We searched PubMed, Crossref, PsycINFO, Scopus, and Google Scholar publications and selected 19 research articles published from 2018 to 2021. Most studies have linked the severity of microcephaly in childbirth to the neurodevelopmental and urinary outcomes in early childhood. However, most children without microcephaly at birth develop typically, while others may be at risk for language impairment.https://www.mdpi.com/1999-4915/13/8/1671Zika virus infectioncongenital Zika syndromecongenital Zika infection and neurodevelopment outcomescongenital Zika infection and neurological outcomescongenital Zika infection and urinary tract disorders |
| spellingShingle | Evangelia Antoniou Eirini Orovou Paraskevi Eva Andronikidi Christos Orovas Nikolaos Rigas Ermioni Palaska Angeliki Sarella Georgios Iatrakis Chrysa Voyiatzaki Congenital Zika Infection and the Risk of Neurodevelopmental, Neurological, and Urinary Track Disorders in Early Childhood. A Systematic Review Viruses Zika virus infection congenital Zika syndrome congenital Zika infection and neurodevelopment outcomes congenital Zika infection and neurological outcomes congenital Zika infection and urinary tract disorders |
| title | Congenital Zika Infection and the Risk of Neurodevelopmental, Neurological, and Urinary Track Disorders in Early Childhood. A Systematic Review |
| title_full | Congenital Zika Infection and the Risk of Neurodevelopmental, Neurological, and Urinary Track Disorders in Early Childhood. A Systematic Review |
| title_fullStr | Congenital Zika Infection and the Risk of Neurodevelopmental, Neurological, and Urinary Track Disorders in Early Childhood. A Systematic Review |
| title_full_unstemmed | Congenital Zika Infection and the Risk of Neurodevelopmental, Neurological, and Urinary Track Disorders in Early Childhood. A Systematic Review |
| title_short | Congenital Zika Infection and the Risk of Neurodevelopmental, Neurological, and Urinary Track Disorders in Early Childhood. A Systematic Review |
| title_sort | congenital zika infection and the risk of neurodevelopmental neurological and urinary track disorders in early childhood a systematic review |
| topic | Zika virus infection congenital Zika syndrome congenital Zika infection and neurodevelopment outcomes congenital Zika infection and neurological outcomes congenital Zika infection and urinary tract disorders |
| url | https://www.mdpi.com/1999-4915/13/8/1671 |
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