Acute T-cell Lymphoblastic Leukemia Presenting with Cardiac Encasement and Pericardial Tamponade
A 52-year-old woman with a history of breast cancer treated previously with doxorubicin, cyclophosphamide, and radiation therapy presented with subacute onset of dyspnea and tachycardia. She was found to have T cell acute lymphoblastic leukemia (T-ALL) with a mediastinal mass encasing the heart and...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Department of Medicine, Warren Alpert Medical School at Brown University
2022-06-01
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| Series: | Brown Journal of Hospital Medicine |
| Online Access: | https://doi.org/10.26300/z494-4f09 |
| _version_ | 1811252641606402048 |
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| author | Rasan Cherala Quynh Lan Dao |
| author_facet | Rasan Cherala Quynh Lan Dao |
| author_sort | Rasan Cherala |
| collection | DOAJ |
| description | A 52-year-old woman with a history of breast cancer treated previously with doxorubicin, cyclophosphamide, and radiation therapy presented with subacute onset of dyspnea and tachycardia. She was found to have T cell acute lymphoblastic leukemia (T-ALL) with a mediastinal mass encasing the heart and a large pericardial effusion with tamponade. We highlight how this rare hematologic malignancy may initially present as pericardial tamponade, and specifically discuss presenting symptoms of subacute pericardial tamponade. Further, we discuss presentation, prognosis and management of T-ALL. |
| first_indexed | 2024-04-12T16:37:38Z |
| format | Article |
| id | doaj.art-75431daefba24c89999da0e024ec5be3 |
| institution | Directory Open Access Journal |
| issn | 2831-5553 |
| language | English |
| last_indexed | 2024-04-12T16:37:38Z |
| publishDate | 2022-06-01 |
| publisher | Department of Medicine, Warren Alpert Medical School at Brown University |
| record_format | Article |
| series | Brown Journal of Hospital Medicine |
| spelling | doaj.art-75431daefba24c89999da0e024ec5be32022-12-22T03:24:56ZengDepartment of Medicine, Warren Alpert Medical School at Brown UniversityBrown Journal of Hospital Medicine2831-55532022-06-0112Acute T-cell Lymphoblastic Leukemia Presenting with Cardiac Encasement and Pericardial TamponadeRasan CheralaQuynh Lan DaoA 52-year-old woman with a history of breast cancer treated previously with doxorubicin, cyclophosphamide, and radiation therapy presented with subacute onset of dyspnea and tachycardia. She was found to have T cell acute lymphoblastic leukemia (T-ALL) with a mediastinal mass encasing the heart and a large pericardial effusion with tamponade. We highlight how this rare hematologic malignancy may initially present as pericardial tamponade, and specifically discuss presenting symptoms of subacute pericardial tamponade. Further, we discuss presentation, prognosis and management of T-ALL.https://doi.org/10.26300/z494-4f09 |
| spellingShingle | Rasan Cherala Quynh Lan Dao Acute T-cell Lymphoblastic Leukemia Presenting with Cardiac Encasement and Pericardial Tamponade Brown Journal of Hospital Medicine |
| title | Acute T-cell Lymphoblastic Leukemia Presenting with Cardiac Encasement and Pericardial Tamponade |
| title_full | Acute T-cell Lymphoblastic Leukemia Presenting with Cardiac Encasement and Pericardial Tamponade |
| title_fullStr | Acute T-cell Lymphoblastic Leukemia Presenting with Cardiac Encasement and Pericardial Tamponade |
| title_full_unstemmed | Acute T-cell Lymphoblastic Leukemia Presenting with Cardiac Encasement and Pericardial Tamponade |
| title_short | Acute T-cell Lymphoblastic Leukemia Presenting with Cardiac Encasement and Pericardial Tamponade |
| title_sort | acute t cell lymphoblastic leukemia presenting with cardiac encasement and pericardial tamponade |
| url | https://doi.org/10.26300/z494-4f09 |
| work_keys_str_mv | AT rasancherala acutetcelllymphoblasticleukemiapresentingwithcardiacencasementandpericardialtamponade AT quynhlandao acutetcelllymphoblasticleukemiapresentingwithcardiacencasementandpericardialtamponade |