SARS-CoV-2 Infection Dysregulates Cilia and Basal Cell Homeostasis in the Respiratory Epithelium of Hamsters

SARS-CoV-2 Infection Dysregulates Cilia and Basal Cell Homeostasis in the Respiratory Epithelium of Hamsters

Similar to many other respiratory viruses, SARS-CoV-2 targets the ciliated cells of the respiratory epithelium and compromises mucociliary clearance, thereby facilitating spread to the lungs and paving the way for secondary infections. A detailed understanding of mechanism involved in ciliary loss a...

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Bibliographic Details
Main Authors: Tom Schreiner, Lisa Allnoch, Georg Beythien, Katarzyna Marek, Kathrin Becker, Dirk Schaudien, Stephanie Stanelle-Bertram, Berfin Schaumburg, Nancy Mounogou Kouassi, Sebastian Beck, Martin Zickler, Gülsah Gabriel, Wolfgang Baumgärtner, Federico Armando, Malgorzata Ciurkiewicz
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
SARS-CoV-2
COVID-19
trachea
golden Syrian hamster
respiratory epithelium
cilia
Online Access:https://www.mdpi.com/1422-0067/23/9/5124

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