Protective effects of calcyclin-binding protein against pulmonary vascular remodeling in flow-associated pulmonary arterial hypertension

Abstract Background Pulmonary arterial hypertension associated with congenital heart disease (CHD-PAH) is recognized as a cancer-like disease with a proliferative and pro-migratory phenotype in pulmonary artery smooth muscle cells (PASMCs). Calcyclin-binding protein/Siah-1-interacting protein (CacyB...

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Bibliographic Details
Main Authors: Jingjing Zhou, FuRong Li, Yicheng Yang
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-022-02137-z