Evaluation of dialysis adequacy based on Kt/V and its related factors among patients undergoing hemodialysis in Guilan dialysis centers
Introduction: Adequate and effective dialysis can improve patients’ quality of life and reduce kidney failure complications and mortality in end-stage renal disease on hemodialysis. Objectives: This study aimed to evaluate dialysis adequacy based on Kt/V and its related factors among patients underg...
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| Format: | Article |
| Language: | English |
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Society of Diabetic Nephropathy Prevention
2022-09-01
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| Series: | Journal of Nephropathology |
| Subjects: | |
| Online Access: | https://nephropathol.com/PDF/jnp-11-e17322.pdf |
| _version_ | 1797828050259279872 |
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| author | Seyyedeh Sahereh Mortazavi Khatibani Maryam Yaseri Haniyeh Sadat Fayazi Elham Ramzanzadeh Azin Hajipoor |
| author_facet | Seyyedeh Sahereh Mortazavi Khatibani Maryam Yaseri Haniyeh Sadat Fayazi Elham Ramzanzadeh Azin Hajipoor |
| author_sort | Seyyedeh Sahereh Mortazavi Khatibani |
| collection | DOAJ |
| description | Introduction: Adequate and effective dialysis can improve patients’ quality of life and reduce kidney failure complications and mortality in end-stage renal disease on hemodialysis. Objectives: This study aimed to evaluate dialysis adequacy based on Kt/V and its related factors among patients undergoing hemodialysis. Patients and Methods: This cross-sectional, multi-center study was conducted during six months on hemodialysis patients referred to dialysis centers of the Guilan province in the north of Iran. Dialysis adequacy was evaluated using Kt/V (>1.2) criteria. Results: The mean Kt/V was 1.24±0.36 with a median of 1.2. Adequacy of dialysis was desirable in 51.2% of the patients. There was a significant and inverse relationship between body mass index (BMI) and Kt/V (r=-0.139, P=0.013). The relationship between Kt/V criterion and pre-dialysis weight (r=-0.310, P=0.00) and post-dialysis weight (r=-0.314, P=0.00) were inverse. The Kt/V criterion was significantly associated with calcium (Ca) level and the patients with normal Ca level had a higher adequacy than those in the other levels of Ca [normal versus low level, mean difference (MD]: 0.19±0.06; normal versus high level, MD: 0.07±0.04, P<0.001). The Kt/V criterion was inversely related to blood pressure and temperature before and after dialysis (P<0.05). Conclusion: The present study showed a close correlation between blood pressure, Ca level and BMI with dialysis adequacy based on Kt/V criteria. The findings obtained here suggested treatment strategies based on correction of Ca levels, BMI and blood pressure prior to dialysis to increase the adequacy of dialysis. |
| first_indexed | 2024-04-09T12:58:14Z |
| format | Article |
| id | doaj.art-754e8d5d2c714919aa2893ffb4403a99 |
| institution | Directory Open Access Journal |
| issn | 2251-8363 2251-8819 |
| language | English |
| last_indexed | 2024-04-09T12:58:14Z |
| publishDate | 2022-09-01 |
| publisher | Society of Diabetic Nephropathy Prevention |
| record_format | Article |
| series | Journal of Nephropathology |
| spelling | doaj.art-754e8d5d2c714919aa2893ffb4403a992023-05-13T11:01:32ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropathology2251-83632251-88192022-09-01114e17322e1732210.34172/jnp.2022.17322jnp-17322Evaluation of dialysis adequacy based on Kt/V and its related factors among patients undergoing hemodialysis in Guilan dialysis centersSeyyedeh Sahereh Mortazavi Khatibani0Maryam Yaseri1Haniyeh Sadat Fayazi2Elham Ramzanzadeh3Azin Hajipoor4Assistant Professor of Internal Medicine, Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, IranAssistant Professor of Internal Medicine, Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, IranAssistant Professor of Internal Medicine, Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, IranAssistant Professor of Internal Medicine, Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, IranAssistant Professor of Internal Medicine, Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, IranIntroduction: Adequate and effective dialysis can improve patients’ quality of life and reduce kidney failure complications and mortality in end-stage renal disease on hemodialysis. Objectives: This study aimed to evaluate dialysis adequacy based on Kt/V and its related factors among patients undergoing hemodialysis. Patients and Methods: This cross-sectional, multi-center study was conducted during six months on hemodialysis patients referred to dialysis centers of the Guilan province in the north of Iran. Dialysis adequacy was evaluated using Kt/V (>1.2) criteria. Results: The mean Kt/V was 1.24±0.36 with a median of 1.2. Adequacy of dialysis was desirable in 51.2% of the patients. There was a significant and inverse relationship between body mass index (BMI) and Kt/V (r=-0.139, P=0.013). The relationship between Kt/V criterion and pre-dialysis weight (r=-0.310, P=0.00) and post-dialysis weight (r=-0.314, P=0.00) were inverse. The Kt/V criterion was significantly associated with calcium (Ca) level and the patients with normal Ca level had a higher adequacy than those in the other levels of Ca [normal versus low level, mean difference (MD]: 0.19±0.06; normal versus high level, MD: 0.07±0.04, P<0.001). The Kt/V criterion was inversely related to blood pressure and temperature before and after dialysis (P<0.05). Conclusion: The present study showed a close correlation between blood pressure, Ca level and BMI with dialysis adequacy based on Kt/V criteria. The findings obtained here suggested treatment strategies based on correction of Ca levels, BMI and blood pressure prior to dialysis to increase the adequacy of dialysis.https://nephropathol.com/PDF/jnp-11-e17322.pdfdialysis adequacychronic kidney failureend-stage renal failure |
| spellingShingle | Seyyedeh Sahereh Mortazavi Khatibani Maryam Yaseri Haniyeh Sadat Fayazi Elham Ramzanzadeh Azin Hajipoor Evaluation of dialysis adequacy based on Kt/V and its related factors among patients undergoing hemodialysis in Guilan dialysis centers Journal of Nephropathology dialysis adequacy chronic kidney failure end-stage renal failure |
| title | Evaluation of dialysis adequacy based on Kt/V and its related factors among patients undergoing hemodialysis in Guilan dialysis centers |
| title_full | Evaluation of dialysis adequacy based on Kt/V and its related factors among patients undergoing hemodialysis in Guilan dialysis centers |
| title_fullStr | Evaluation of dialysis adequacy based on Kt/V and its related factors among patients undergoing hemodialysis in Guilan dialysis centers |
| title_full_unstemmed | Evaluation of dialysis adequacy based on Kt/V and its related factors among patients undergoing hemodialysis in Guilan dialysis centers |
| title_short | Evaluation of dialysis adequacy based on Kt/V and its related factors among patients undergoing hemodialysis in Guilan dialysis centers |
| title_sort | evaluation of dialysis adequacy based on kt v and its related factors among patients undergoing hemodialysis in guilan dialysis centers |
| topic | dialysis adequacy chronic kidney failure end-stage renal failure |
| url | https://nephropathol.com/PDF/jnp-11-e17322.pdf |
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