The 2022 West Nile Virus Season in Greece; A Quite Intense Season
Since 2010, the West Nile virus (WNV) has been established in Greece. We describe the epidemiology of diagnosed human WNV infections in Greece with a focus on the 2022 season. During the transmission period, clinicians were sending samples from suspected cases for testing. Active laboratory-based su...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/15/7/1481 |
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| author | Danai Pervanidou Chrysovaladou Niki Kefaloudi Anna Vakali Ourania Tsakalidou Myrsini Karatheodorou Katerina Tsioka Maria Evangelidou Kassiani Mellou Styliani Pappa Konstantina Stoikou Vasiliki Bakaloudi George Koliopoulos Kostas Stamoulis Eleni Patsoula Constantina Politis Christos Hadjichristodoulou Anna Papa |
| author_facet | Danai Pervanidou Chrysovaladou Niki Kefaloudi Anna Vakali Ourania Tsakalidou Myrsini Karatheodorou Katerina Tsioka Maria Evangelidou Kassiani Mellou Styliani Pappa Konstantina Stoikou Vasiliki Bakaloudi George Koliopoulos Kostas Stamoulis Eleni Patsoula Constantina Politis Christos Hadjichristodoulou Anna Papa |
| author_sort | Danai Pervanidou |
| collection | DOAJ |
| description | Since 2010, the West Nile virus (WNV) has been established in Greece. We describe the epidemiology of diagnosed human WNV infections in Greece with a focus on the 2022 season. During the transmission period, clinicians were sending samples from suspected cases for testing. Active laboratory-based surveillance was performed with immediate notification of diagnosed cases. We collected clinical information and interviewed patients on a timely basis to identify their place of exposure. Besides serological and molecular diagnostic methods, next-generation sequencing was also performed. In 2022, 286 cases of WNV infection were diagnosed, including 278 symptomatic cases and 184 (64%) cases with neuroinvasive disease (WNND); 33 patients died. This was the third most intense season concerning the number of WNND cases, following 2018 and 2010. Most (96%) cases were recorded in two regions, in northern and central Greece. The virus strain was a variant of previous years, clustering into the Central European subclade of WNV lineage 2. The 2022 WNV season was quite intense in Greece. The prompt diagnosis and investigation of cases are considered pivotal for the timely response, while the availability of whole genome sequences enables studies on the molecular epidemiology of the disease. |
| first_indexed | 2024-03-11T00:34:15Z |
| format | Article |
| id | doaj.art-754f133b7226483eb1ff0bfe0c24b2f6 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-11T00:34:15Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-754f133b7226483eb1ff0bfe0c24b2f62023-11-18T21:44:18ZengMDPI AGViruses1999-49152023-06-01157148110.3390/v15071481The 2022 West Nile Virus Season in Greece; A Quite Intense SeasonDanai Pervanidou0Chrysovaladou Niki Kefaloudi1Anna Vakali2Ourania Tsakalidou3Myrsini Karatheodorou4Katerina Tsioka5Maria Evangelidou6Kassiani Mellou7Styliani Pappa8Konstantina Stoikou9Vasiliki Bakaloudi10George Koliopoulos11Kostas Stamoulis12Eleni Patsoula13Constantina Politis14Christos Hadjichristodoulou15Anna Papa16National Public Health Organization (EODY), 151 23 Athens, GreeceNational Public Health Organization (EODY), 151 23 Athens, GreeceNational Public Health Organization (EODY), 151 23 Athens, GreeceNational Reference Center for Arboviruses and Haemorrhagic Fever Viruses, Department of Microbiology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, GreeceNational Reference Center for Arboviruses and Haemorrhagic Fever Viruses, Department of Microbiology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, GreeceNational Reference Center for Arboviruses and Haemorrhagic Fever Viruses, Department of Microbiology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, GreeceHellenic Pasteur Institute, 115 21 Athens, GreeceNational Public Health Organization (EODY), 151 23 Athens, GreeceNational Reference Center for Arboviruses and Haemorrhagic Fever Viruses, Department of Microbiology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, GreeceNational Reference Center for Arboviruses and Haemorrhagic Fever Viruses, Department of Microbiology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, GreeceMolecular Blood Center, AHEPA University General Hospital, 546 36 Thessaloniki, GreeceDepartment of Crop Science, School of Plant Sciences, Agricultural University of Athens, 118 55 Athens, GreeceHellenic National Blood Transfusion Center, 136 72 Athens, GreeceDepartment of Public Health Policy, School of Public Health, University of West Attica, 115 21 Athens, GreeceNational Public Health Organization (EODY), 151 23 Athens, GreeceDepartment of Hygiene and Epidemiology, School of Health Sciences, Faculty of Medicine, University of Thessaly, 412 22 Larisa, GreeceNational Reference Center for Arboviruses and Haemorrhagic Fever Viruses, Department of Microbiology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, GreeceSince 2010, the West Nile virus (WNV) has been established in Greece. We describe the epidemiology of diagnosed human WNV infections in Greece with a focus on the 2022 season. During the transmission period, clinicians were sending samples from suspected cases for testing. Active laboratory-based surveillance was performed with immediate notification of diagnosed cases. We collected clinical information and interviewed patients on a timely basis to identify their place of exposure. Besides serological and molecular diagnostic methods, next-generation sequencing was also performed. In 2022, 286 cases of WNV infection were diagnosed, including 278 symptomatic cases and 184 (64%) cases with neuroinvasive disease (WNND); 33 patients died. This was the third most intense season concerning the number of WNND cases, following 2018 and 2010. Most (96%) cases were recorded in two regions, in northern and central Greece. The virus strain was a variant of previous years, clustering into the Central European subclade of WNV lineage 2. The 2022 WNV season was quite intense in Greece. The prompt diagnosis and investigation of cases are considered pivotal for the timely response, while the availability of whole genome sequences enables studies on the molecular epidemiology of the disease.https://www.mdpi.com/1999-4915/15/7/1481West Nile virusGreecemosquito-borne diseasevector-borne disease |
| spellingShingle | Danai Pervanidou Chrysovaladou Niki Kefaloudi Anna Vakali Ourania Tsakalidou Myrsini Karatheodorou Katerina Tsioka Maria Evangelidou Kassiani Mellou Styliani Pappa Konstantina Stoikou Vasiliki Bakaloudi George Koliopoulos Kostas Stamoulis Eleni Patsoula Constantina Politis Christos Hadjichristodoulou Anna Papa The 2022 West Nile Virus Season in Greece; A Quite Intense Season Viruses West Nile virus Greece mosquito-borne disease vector-borne disease |
| title | The 2022 West Nile Virus Season in Greece; A Quite Intense Season |
| title_full | The 2022 West Nile Virus Season in Greece; A Quite Intense Season |
| title_fullStr | The 2022 West Nile Virus Season in Greece; A Quite Intense Season |
| title_full_unstemmed | The 2022 West Nile Virus Season in Greece; A Quite Intense Season |
| title_short | The 2022 West Nile Virus Season in Greece; A Quite Intense Season |
| title_sort | 2022 west nile virus season in greece a quite intense season |
| topic | West Nile virus Greece mosquito-borne disease vector-borne disease |
| url | https://www.mdpi.com/1999-4915/15/7/1481 |
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