Gamma, E-Beam and X-ray Irradiations on PE/EVOH/PE Multilayer Film: An Industrial Point of View Regarding the Impact on Mechanical Properties

X-ray and electron-beam (E-beam) sterilization technologies were assessed to supplement gamma sterilization, the most common radiation technology used today for biopharmaceutical product sterilization. The mechanical properties of a PE/EVOH/PE film were studied using tensile tests and dynamical mech...

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Main Authors: Nina Girard-Perier, Sylvain R. A. Marque, Nathalie Dupuy, Blanche Krieguer, Samuel Dorey
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/15/13/2799
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author Nina Girard-Perier
Sylvain R. A. Marque
Nathalie Dupuy
Blanche Krieguer
Samuel Dorey
author_facet Nina Girard-Perier
Sylvain R. A. Marque
Nathalie Dupuy
Blanche Krieguer
Samuel Dorey
author_sort Nina Girard-Perier
collection DOAJ
description X-ray and electron-beam (E-beam) sterilization technologies were assessed to supplement gamma sterilization, the most common radiation technology used today for biopharmaceutical product sterilization. The mechanical properties of a PE/EVOH/PE film were studied using tensile tests and dynamical mechanical analysis after each irradiation technology (i.e., gamma, electron beam and X-ray irradiations). The effects of each irradiation were compared using two statistical methods. The results indicate that the three irradiation technologies induce no difference in mechanical properties in the investigated dose range for this material.
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spelling doaj.art-754fd438c5b94ffda931944696830bb82023-11-18T17:20:15ZengMDPI AGPolymers2073-43602023-06-011513279910.3390/polym15132799Gamma, E-Beam and X-ray Irradiations on PE/EVOH/PE Multilayer Film: An Industrial Point of View Regarding the Impact on Mechanical PropertiesNina Girard-Perier0Sylvain R. A. Marque1Nathalie Dupuy2Blanche Krieguer3Samuel Dorey4Sartorius Stedim FMT S.A.S, Z.I. Les Paluds, Avenue de Jouques CS91051, CEDEX, 13781 Aubagne, FranceAix Marseille Univ, CNRS, ICR, Case 551, 13397 Marseille, FranceAix Marseille Univ, Avignon Université, CNRS, IRD, IMBE, 13013 Marseille, FranceSartorius Stedim FMT S.A.S, Z.I. Les Paluds, Avenue de Jouques CS91051, CEDEX, 13781 Aubagne, FranceSartorius Stedim FMT S.A.S, Z.I. Les Paluds, Avenue de Jouques CS91051, CEDEX, 13781 Aubagne, FranceX-ray and electron-beam (E-beam) sterilization technologies were assessed to supplement gamma sterilization, the most common radiation technology used today for biopharmaceutical product sterilization. The mechanical properties of a PE/EVOH/PE film were studied using tensile tests and dynamical mechanical analysis after each irradiation technology (i.e., gamma, electron beam and X-ray irradiations). The effects of each irradiation were compared using two statistical methods. The results indicate that the three irradiation technologies induce no difference in mechanical properties in the investigated dose range for this material.https://www.mdpi.com/2073-4360/15/13/2799irradiation technologygammaX-rayspolyethylenemechanical propertiesthermal and viscoelastic properties
spellingShingle Nina Girard-Perier
Sylvain R. A. Marque
Nathalie Dupuy
Blanche Krieguer
Samuel Dorey
Gamma, E-Beam and X-ray Irradiations on PE/EVOH/PE Multilayer Film: An Industrial Point of View Regarding the Impact on Mechanical Properties
Polymers
irradiation technology
gamma
X-rays
polyethylene
mechanical properties
thermal and viscoelastic properties
title Gamma, E-Beam and X-ray Irradiations on PE/EVOH/PE Multilayer Film: An Industrial Point of View Regarding the Impact on Mechanical Properties
title_full Gamma, E-Beam and X-ray Irradiations on PE/EVOH/PE Multilayer Film: An Industrial Point of View Regarding the Impact on Mechanical Properties
title_fullStr Gamma, E-Beam and X-ray Irradiations on PE/EVOH/PE Multilayer Film: An Industrial Point of View Regarding the Impact on Mechanical Properties
title_full_unstemmed Gamma, E-Beam and X-ray Irradiations on PE/EVOH/PE Multilayer Film: An Industrial Point of View Regarding the Impact on Mechanical Properties
title_short Gamma, E-Beam and X-ray Irradiations on PE/EVOH/PE Multilayer Film: An Industrial Point of View Regarding the Impact on Mechanical Properties
title_sort gamma e beam and x ray irradiations on pe evoh pe multilayer film an industrial point of view regarding the impact on mechanical properties
topic irradiation technology
gamma
X-rays
polyethylene
mechanical properties
thermal and viscoelastic properties
url https://www.mdpi.com/2073-4360/15/13/2799
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