A comparison of the time course of action and laryngeal mask airway insertion conditions with different doses of mivacurium for day-case urologic surgery in children: a prospective cohort study
ObjectiveTo investigate the time course of action of different doses of mivacurium and determine the appropriate dose for laryngeal mask airway (LMA) insertion for day-case urologic surgery in children.MethodsA total of 105 patients who enrolled in this study between March 2021 and December 2021 wer...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-02-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2024.1330737/full |
| _version_ | 1827341478323552256 |
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| author | Hong Ye Chunmiao Nian Lijun Zhou Yuman Xie Fan Li Tao Xue Xueping Han |
| author_facet | Hong Ye Chunmiao Nian Lijun Zhou Yuman Xie Fan Li Tao Xue Xueping Han |
| author_sort | Hong Ye |
| collection | DOAJ |
| description | ObjectiveTo investigate the time course of action of different doses of mivacurium and determine the appropriate dose for laryngeal mask airway (LMA) insertion for day-case urologic surgery in children.MethodsA total of 105 patients who enrolled in this study between March 2021 and December 2021 were randomised into 3 groups: Group A (mivacurium 0.15 mg/kg, n = 35), Group B (mivacurium 0.20 mg/kg, n = 35) and Group C (mivacurium 0.25 mg/kg, n = 35). The different doses of mivacurium were injected before LMA insertion. The primary outcomes included the grading of conditions for the LMA insertion-18 score, onset time, recovery index and the duration that mivacurium was effective. Secondary outcomes included pulse oxygen saturation, mean blood pressure, heart rate and the incidence of adverse events.ResultsThe score of the conditions for LMA insertion in Group A was significantly lower than in Groups C and B (p < 0.005). There was a significant difference in the onset time between Groups B and A (p < 0.005). There was no significant difference in the overall incidence of adverse reactions between these groups (p > 0.05).ConclusionAnaesthesia with 0.2 mg/kg of mivacurium can effectively shorten the onset time and facilitate insertion of the LMA in children undergoing day-case urologic surgery. |
| first_indexed | 2024-03-07T21:42:34Z |
| format | Article |
| id | doaj.art-75505a45d38a4c439e5c5786c70a4ac2 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-03-07T21:42:34Z |
| publishDate | 2024-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-75505a45d38a4c439e5c5786c70a4ac22024-02-26T04:52:13ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602024-02-011210.3389/fped.2024.13307371330737A comparison of the time course of action and laryngeal mask airway insertion conditions with different doses of mivacurium for day-case urologic surgery in children: a prospective cohort studyHong YeChunmiao NianLijun ZhouYuman XieFan LiTao XueXueping HanObjectiveTo investigate the time course of action of different doses of mivacurium and determine the appropriate dose for laryngeal mask airway (LMA) insertion for day-case urologic surgery in children.MethodsA total of 105 patients who enrolled in this study between March 2021 and December 2021 were randomised into 3 groups: Group A (mivacurium 0.15 mg/kg, n = 35), Group B (mivacurium 0.20 mg/kg, n = 35) and Group C (mivacurium 0.25 mg/kg, n = 35). The different doses of mivacurium were injected before LMA insertion. The primary outcomes included the grading of conditions for the LMA insertion-18 score, onset time, recovery index and the duration that mivacurium was effective. Secondary outcomes included pulse oxygen saturation, mean blood pressure, heart rate and the incidence of adverse events.ResultsThe score of the conditions for LMA insertion in Group A was significantly lower than in Groups C and B (p < 0.005). There was a significant difference in the onset time between Groups B and A (p < 0.005). There was no significant difference in the overall incidence of adverse reactions between these groups (p > 0.05).ConclusionAnaesthesia with 0.2 mg/kg of mivacurium can effectively shorten the onset time and facilitate insertion of the LMA in children undergoing day-case urologic surgery.https://www.frontiersin.org/articles/10.3389/fped.2024.1330737/fullmivacuriumday-case surgeryurologic surgery in childrenlaryngeal mask airwayanesthesiology |
| spellingShingle | Hong Ye Chunmiao Nian Lijun Zhou Yuman Xie Fan Li Tao Xue Xueping Han A comparison of the time course of action and laryngeal mask airway insertion conditions with different doses of mivacurium for day-case urologic surgery in children: a prospective cohort study Frontiers in Pediatrics mivacurium day-case surgery urologic surgery in children laryngeal mask airway anesthesiology |
| title | A comparison of the time course of action and laryngeal mask airway insertion conditions with different doses of mivacurium for day-case urologic surgery in children: a prospective cohort study |
| title_full | A comparison of the time course of action and laryngeal mask airway insertion conditions with different doses of mivacurium for day-case urologic surgery in children: a prospective cohort study |
| title_fullStr | A comparison of the time course of action and laryngeal mask airway insertion conditions with different doses of mivacurium for day-case urologic surgery in children: a prospective cohort study |
| title_full_unstemmed | A comparison of the time course of action and laryngeal mask airway insertion conditions with different doses of mivacurium for day-case urologic surgery in children: a prospective cohort study |
| title_short | A comparison of the time course of action and laryngeal mask airway insertion conditions with different doses of mivacurium for day-case urologic surgery in children: a prospective cohort study |
| title_sort | comparison of the time course of action and laryngeal mask airway insertion conditions with different doses of mivacurium for day case urologic surgery in children a prospective cohort study |
| topic | mivacurium day-case surgery urologic surgery in children laryngeal mask airway anesthesiology |
| url | https://www.frontiersin.org/articles/10.3389/fped.2024.1330737/full |
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