Upregulation of CIRP by its agonist prevents the development of heart failure in myocardial infarction rats

Upregulation of CIRP by its agonist prevents the development of heart failure in myocardial infarction rats

Abstract Background Downregulated expression of cold-inducible RNA binding protein (CIRP), a stress-response protein, has been demonstrated in the hearts of patients with heart failure (HF). However, whether CIRP plays a critical role in the pathogenesis of HF remains unknown. Zr17-2 is a recently i...

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Bibliographic Details
Main Authors: Jingjing Zhang, Tao Liu, Yanzhao Wei, Jianye Peng, Gaofeng Zeng, Peng Zhong
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Cardiovascular Disorders
Subjects:
CIRP
Myocardial infarction
zr17-2
Inflammation
Nrf2
Online Access:https://doi.org/10.1186/s12872-024-03852-9

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