Lantern-shaped screw loaded with autologous bone for treating osteonecrosis of the femoral head
Abstract Background Treatment for osteonecrosis of the femoral head (ONFH) in young individuals remains controversial. We developed a lantern-shaped screw, which was designed to provide mechanical support for the femoral head to prevent its collapse, for the treatment of ONFH. The purpose of this st...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2018-09-01
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| Series: | BMC Musculoskeletal Disorders |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12891-018-2243-z |
| _version_ | 1819261975474995200 |
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| author | Dasheng Lin Lei Wang Zhaoliang Yu Deqing Luo Xigui Zhang Kejian Lian |
| author_facet | Dasheng Lin Lei Wang Zhaoliang Yu Deqing Luo Xigui Zhang Kejian Lian |
| author_sort | Dasheng Lin |
| collection | DOAJ |
| description | Abstract Background Treatment for osteonecrosis of the femoral head (ONFH) in young individuals remains controversial. We developed a lantern-shaped screw, which was designed to provide mechanical support for the femoral head to prevent its collapse, for the treatment of ONFH. The purpose of this study was to investigate the efficacy and safety of the lantern-shaped screw loaded with autologous bone for the treatment of pre-collapse stages of ONFH. Methods Thirty-two patients were randomly divided into two groups: the lantern-shaped screw group (core decompression and lantern-shaped screw loaded with autogenous bone) and the control group (core decompression and autogenous bone graft). During 36 months follow-up after surgery, treatment results in patients were assessed by X-ray and computed tomography (CT) scanning as well as functional recovery Harris hip score (HHS). Results Successful clinical results were achieved in 15 of 16 hips (94%) in the lantern-shaped screw group compared with 10 of 16 hips (63%) in the control group (p = 0.0325). Successful radiological results were achieved in 14 of 16 hips (88%) in the lantern-shaped screw group compared with 8 of 16 hips (50%) in the control group (P = 0.0221). Conclusion The lantern-shaped screw loaded with autologous bone for the treatment of pre-collapse stages of ONFH is effective and results in preventing progression of ONFH and reducing the risk of femoral head collapse. Trial registration The trial registration number: ChiCTR-TRC-13004078 (retrospectively registered at 2013-11-28). |
| first_indexed | 2024-12-23T19:50:20Z |
| format | Article |
| id | doaj.art-7554e1febc574335867306125c566f3e |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-12-23T19:50:20Z |
| publishDate | 2018-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-7554e1febc574335867306125c566f3e2022-12-21T17:33:24ZengBMCBMC Musculoskeletal Disorders1471-24742018-09-011911710.1186/s12891-018-2243-zLantern-shaped screw loaded with autologous bone for treating osteonecrosis of the femoral headDasheng Lin0Lei Wang1Zhaoliang Yu2Deqing Luo3Xigui Zhang4Kejian Lian5Orthopaedic Center of People’s Liberation Army, The Affiliated Southeast Hospital of Xiamen UniversityOrthopaedic Center of People’s Liberation Army, The Affiliated Southeast Hospital of Xiamen UniversityWeigao Orthopaedic Device Co., LtdOrthopaedic Center of People’s Liberation Army, The Affiliated Southeast Hospital of Xiamen UniversityDouble Engine Medical Material Co., LtdOrthopaedic Center of People’s Liberation Army, The Affiliated Southeast Hospital of Xiamen UniversityAbstract Background Treatment for osteonecrosis of the femoral head (ONFH) in young individuals remains controversial. We developed a lantern-shaped screw, which was designed to provide mechanical support for the femoral head to prevent its collapse, for the treatment of ONFH. The purpose of this study was to investigate the efficacy and safety of the lantern-shaped screw loaded with autologous bone for the treatment of pre-collapse stages of ONFH. Methods Thirty-two patients were randomly divided into two groups: the lantern-shaped screw group (core decompression and lantern-shaped screw loaded with autogenous bone) and the control group (core decompression and autogenous bone graft). During 36 months follow-up after surgery, treatment results in patients were assessed by X-ray and computed tomography (CT) scanning as well as functional recovery Harris hip score (HHS). Results Successful clinical results were achieved in 15 of 16 hips (94%) in the lantern-shaped screw group compared with 10 of 16 hips (63%) in the control group (p = 0.0325). Successful radiological results were achieved in 14 of 16 hips (88%) in the lantern-shaped screw group compared with 8 of 16 hips (50%) in the control group (P = 0.0221). Conclusion The lantern-shaped screw loaded with autologous bone for the treatment of pre-collapse stages of ONFH is effective and results in preventing progression of ONFH and reducing the risk of femoral head collapse. Trial registration The trial registration number: ChiCTR-TRC-13004078 (retrospectively registered at 2013-11-28).http://link.springer.com/article/10.1186/s12891-018-2243-zLantern-shaped screwAutogenous bone graftCore decompressionOsteonecrosis of the femoral head |
| spellingShingle | Dasheng Lin Lei Wang Zhaoliang Yu Deqing Luo Xigui Zhang Kejian Lian Lantern-shaped screw loaded with autologous bone for treating osteonecrosis of the femoral head BMC Musculoskeletal Disorders Lantern-shaped screw Autogenous bone graft Core decompression Osteonecrosis of the femoral head |
| title | Lantern-shaped screw loaded with autologous bone for treating osteonecrosis of the femoral head |
| title_full | Lantern-shaped screw loaded with autologous bone for treating osteonecrosis of the femoral head |
| title_fullStr | Lantern-shaped screw loaded with autologous bone for treating osteonecrosis of the femoral head |
| title_full_unstemmed | Lantern-shaped screw loaded with autologous bone for treating osteonecrosis of the femoral head |
| title_short | Lantern-shaped screw loaded with autologous bone for treating osteonecrosis of the femoral head |
| title_sort | lantern shaped screw loaded with autologous bone for treating osteonecrosis of the femoral head |
| topic | Lantern-shaped screw Autogenous bone graft Core decompression Osteonecrosis of the femoral head |
| url | http://link.springer.com/article/10.1186/s12891-018-2243-z |
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