Oral changes in patients before and after transplantation of solid organs and hematopoietic stem cells
Introduction/Objective. The aim of this paper is to point out the prevalence and severity of oral diseases in patients in the period before and after the transplantation of solid organs and hematopoietic stem cells. Methods. MEDLINE literature search was done via PubMed. Results. The development and...
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| Format: | Article |
| Language: | English |
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Serbian Medical Society
2021-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2021/0370-81792000106J.pdf |
| _version_ | 1818742981813862400 |
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| author | Jovičić Olivera Mandić Jelena Mandinić Zoran Čolović Aleksandra |
| author_facet | Jovičić Olivera Mandić Jelena Mandinić Zoran Čolović Aleksandra |
| author_sort | Jovičić Olivera |
| collection | DOAJ |
| description | Introduction/Objective. The aim of this paper is to point out the prevalence and severity of oral diseases in patients in the period before and after the transplantation of solid organs and hematopoietic stem cells. Methods. MEDLINE literature search was done via PubMed. Results. The development and improvement of transplantation medicine in specialized centers lead to an increasing number of patients, both adults and children, with transplanted solid organs and hematopoietic stem cells. Despite the success of therapy, numerous changes and complications can be observed on other organs in patients undergoing transplantation of solid organs and hematopoietic stem cells in the pre- and post-transplant phase. Systemic diseases and conditions related to organ and cell transplantation, which are accompanied by numerous oral manifestations. The most common oral changes are gingival enlargement, desquamation of the oral epithelium, very painful ulcerations, polypoid and granulomatous changes in the oral mucosa, hard dental tissues with frequent complications, developmental anomalies of teeth in younger children, and in the later stage also the occurrence of oral cancer. After transplantation of solid organs, hematopoietic changes in the oral cavity and other organs occur depending on the patient’s post-transplantation period as well as on the applied immunosuppressive therapy. Conclusion. Oral changes development before and after transplantation of solid organs and hematopoietic stem cells point to the importance of timely and competent cooperation between the dentist and the doctor who treats the underlying disease. |
| first_indexed | 2024-12-18T02:21:09Z |
| format | Article |
| id | doaj.art-755b48a302634ba993e6097ac99b2a44 |
| institution | Directory Open Access Journal |
| issn | 0370-8179 2406-0895 |
| language | English |
| last_indexed | 2024-12-18T02:21:09Z |
| publishDate | 2021-01-01 |
| publisher | Serbian Medical Society |
| record_format | Article |
| series | Srpski Arhiv za Celokupno Lekarstvo |
| spelling | doaj.art-755b48a302634ba993e6097ac99b2a442022-12-21T21:24:11ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792406-08952021-01-011495-638138610.2298/SARH190909106J0370-81792000106JOral changes in patients before and after transplantation of solid organs and hematopoietic stem cellsJovičić Olivera0Mandić Jelena1https://orcid.org/0000-0002-4726-6450Mandinić Zoran2https://orcid.org/0000-0003-2622-6043Čolović Aleksandra3https://orcid.org/0000-0001-9057-2501University of Belgrade, School of Dental Medicine, Clinic for Pediatric and Preventive Dentistry, Belgrade, SerbiaUniversity of Belgrade, School of Dental Medicine, Clinic for Pediatric and Preventive Dentistry, Belgrade, SerbiaUniversity of Belgrade, School of Dental Medicine, Clinic for Pediatric and Preventive Dentistry, Belgrade, SerbiaUniversity of Belgrade, School of Dental Medicine, Clinic for Pediatric and Preventive Dentistry, Belgrade, SerbiaIntroduction/Objective. The aim of this paper is to point out the prevalence and severity of oral diseases in patients in the period before and after the transplantation of solid organs and hematopoietic stem cells. Methods. MEDLINE literature search was done via PubMed. Results. The development and improvement of transplantation medicine in specialized centers lead to an increasing number of patients, both adults and children, with transplanted solid organs and hematopoietic stem cells. Despite the success of therapy, numerous changes and complications can be observed on other organs in patients undergoing transplantation of solid organs and hematopoietic stem cells in the pre- and post-transplant phase. Systemic diseases and conditions related to organ and cell transplantation, which are accompanied by numerous oral manifestations. The most common oral changes are gingival enlargement, desquamation of the oral epithelium, very painful ulcerations, polypoid and granulomatous changes in the oral mucosa, hard dental tissues with frequent complications, developmental anomalies of teeth in younger children, and in the later stage also the occurrence of oral cancer. After transplantation of solid organs, hematopoietic changes in the oral cavity and other organs occur depending on the patient’s post-transplantation period as well as on the applied immunosuppressive therapy. Conclusion. Oral changes development before and after transplantation of solid organs and hematopoietic stem cells point to the importance of timely and competent cooperation between the dentist and the doctor who treats the underlying disease.http://www.doiserbia.nb.rs/img/doi/0370-8179/2021/0370-81792000106J.pdforgan transplantationhematopoietic stem cell transplantationoral diseases |
| spellingShingle | Jovičić Olivera Mandić Jelena Mandinić Zoran Čolović Aleksandra Oral changes in patients before and after transplantation of solid organs and hematopoietic stem cells Srpski Arhiv za Celokupno Lekarstvo organ transplantation hematopoietic stem cell transplantation oral diseases |
| title | Oral changes in patients before and after transplantation of solid organs and hematopoietic stem cells |
| title_full | Oral changes in patients before and after transplantation of solid organs and hematopoietic stem cells |
| title_fullStr | Oral changes in patients before and after transplantation of solid organs and hematopoietic stem cells |
| title_full_unstemmed | Oral changes in patients before and after transplantation of solid organs and hematopoietic stem cells |
| title_short | Oral changes in patients before and after transplantation of solid organs and hematopoietic stem cells |
| title_sort | oral changes in patients before and after transplantation of solid organs and hematopoietic stem cells |
| topic | organ transplantation hematopoietic stem cell transplantation oral diseases |
| url | http://www.doiserbia.nb.rs/img/doi/0370-8179/2021/0370-81792000106J.pdf |
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