Comparison Between Virulence Factors of Candida albicans and Non-Albicans Species of Candida Isolated from Genitourinary Tract
Background: Candida spp. is frequently isolated from cases of vulvovaginal candidiasis and catheter associated UTI. C.albicans is the most frequently isolated species but non-albicans species of candida are gaining clinical significance. Objectives: To compare the virulence factors like biofilm...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2014-11-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/5137/10121_CE(Ra)_F(Sh)_PF1(SNAK)_PFA(Sh).pdf |
| _version_ | 1818444656862560256 |
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| author | Udayalaxmi Shani Jacob Diney D’Souza |
| author_facet | Udayalaxmi Shani Jacob Diney D’Souza |
| author_sort | Udayalaxmi |
| collection | DOAJ |
| description | Background: Candida spp. is frequently isolated from cases of
vulvovaginal candidiasis and catheter associated UTI. C.albicans
is the most frequently isolated species but non-albicans species
of candida are gaining clinical significance.
Objectives: To compare the virulence factors like biofilm
production, phospholipase and hemolytic activity in C.albicans
with that of non albicans species of candida isolated from
urogenital tract.
Materials and Methods: Vaginal swabs and urine samples
received in Microbiology laboratory during one year period were
processed by standard methods. The candida isolates were
speciated and biofilm production, phospholipase and hemolytic
activity were studied in them. Statistical analysis was performed
using SPSS version 11.5.
Results: Out of the 3001 urine samples processed 41 (1.3%)
were positive for candida, out of 293 high vaginal swabs 41(14%)
were positive for candida. C.albicans was the most prevalent
isolate followed by C.tropicalis, C.glabrata and C.krusei. Out of
40 C.albicans strains, 22 (55%) produced biofilm, 39 (97.5%)
produced hemolysin and 21 (52.5%) produced phospholipase.
Out of 42 strains of non albicans species of candida, 19 (45%)
produced biofilm, 41(97.6%) hemolysin and 5 (12%) produced
phospholipase.
Conclusion: Phospholipase production was better in C.albicans
in comparison toother species of candida. There was no
statistically relevant difference between hemolysin and biofilm
production by C.albicans and non albicans strains of candida. |
| first_indexed | 2024-12-14T19:19:25Z |
| format | Article |
| id | doaj.art-7561be54205442fa81dd78a59b642fc7 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-14T19:19:25Z |
| publishDate | 2014-11-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-7561be54205442fa81dd78a59b642fc72022-12-21T22:50:25ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-11-01811DC15DC1710.7860/JCDR/2014/10121.5137Comparison Between Virulence Factors of Candida albicans and Non-Albicans Species of Candida Isolated from Genitourinary TractUdayalaxmi0Shani Jacob1Diney D’Souza2Selection Grade Lecturer, Department of Microbiology, KMC, Manipal University, Mangalore, India.Post Graduate Students, Department of Microbiology, KMC, Manipal University, Mangalore, India.Post Graduate Students, Department of Microbiology, KMC, Manipal University, Mangalore, India.Background: Candida spp. is frequently isolated from cases of vulvovaginal candidiasis and catheter associated UTI. C.albicans is the most frequently isolated species but non-albicans species of candida are gaining clinical significance. Objectives: To compare the virulence factors like biofilm production, phospholipase and hemolytic activity in C.albicans with that of non albicans species of candida isolated from urogenital tract. Materials and Methods: Vaginal swabs and urine samples received in Microbiology laboratory during one year period were processed by standard methods. The candida isolates were speciated and biofilm production, phospholipase and hemolytic activity were studied in them. Statistical analysis was performed using SPSS version 11.5. Results: Out of the 3001 urine samples processed 41 (1.3%) were positive for candida, out of 293 high vaginal swabs 41(14%) were positive for candida. C.albicans was the most prevalent isolate followed by C.tropicalis, C.glabrata and C.krusei. Out of 40 C.albicans strains, 22 (55%) produced biofilm, 39 (97.5%) produced hemolysin and 21 (52.5%) produced phospholipase. Out of 42 strains of non albicans species of candida, 19 (45%) produced biofilm, 41(97.6%) hemolysin and 5 (12%) produced phospholipase. Conclusion: Phospholipase production was better in C.albicans in comparison toother species of candida. There was no statistically relevant difference between hemolysin and biofilm production by C.albicans and non albicans strains of candida.https://jcdr.net/articles/PDF/5137/10121_CE(Ra)_F(Sh)_PF1(SNAK)_PFA(Sh).pdfbiofilm productioncandidahemolytic activityphospholipaseurogenital tract |
| spellingShingle | Udayalaxmi Shani Jacob Diney D’Souza Comparison Between Virulence Factors of Candida albicans and Non-Albicans Species of Candida Isolated from Genitourinary Tract Journal of Clinical and Diagnostic Research biofilm production candida hemolytic activity phospholipase urogenital tract |
| title | Comparison Between Virulence Factors of Candida albicans and Non-Albicans Species of Candida Isolated from Genitourinary Tract |
| title_full | Comparison Between Virulence Factors of Candida albicans and Non-Albicans Species of Candida Isolated from Genitourinary Tract |
| title_fullStr | Comparison Between Virulence Factors of Candida albicans and Non-Albicans Species of Candida Isolated from Genitourinary Tract |
| title_full_unstemmed | Comparison Between Virulence Factors of Candida albicans and Non-Albicans Species of Candida Isolated from Genitourinary Tract |
| title_short | Comparison Between Virulence Factors of Candida albicans and Non-Albicans Species of Candida Isolated from Genitourinary Tract |
| title_sort | comparison between virulence factors of candida albicans and non albicans species of candida isolated from genitourinary tract |
| topic | biofilm production candida hemolytic activity phospholipase urogenital tract |
| url | https://jcdr.net/articles/PDF/5137/10121_CE(Ra)_F(Sh)_PF1(SNAK)_PFA(Sh).pdf |
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