Antiviral response elicited against avian influenza virus infection following activation of toll-like receptor (TLR)7 signaling pathway is attributable to interleukin (IL)-1β production

Antiviral response elicited against avian influenza virus infection following activation of toll-like receptor (TLR)7 signaling pathway is attributable to interleukin (IL)-1β production

Abstract Objective Single stranded ribonucleic acid (ssRNA) binds to toll-like receptor (TLR)7 leading to recruitment of immune cells and production of pro-inflammatory cytokines, which has been shown in mammals. In chickens, ssRNA has been shown to elicit antiviral response against infectious bursa...

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Bibliographic Details
Main Authors: Mohamed Sarjoon Abdul-Cader, Upasama De Silva Senapathi, Eva Nagy, Shayan Sharif, Mohamed Faizal Abdul-Careem
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Research Notes
Subjects:
Resiquimod
ssRNA
Macrophage
Avian influenza virus
Nitric oxide
Interleukin 1β
Online Access:http://link.springer.com/article/10.1186/s13104-018-3975-4

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