Chronic hepatitis C virus infection irreversibly impacts human natural killer cell repertoire diversity

Chronic hepatitis C virus infection irreversibly impacts human natural killer cell repertoire diversity

Natural killer (NK) cells are important immune cells for mediating antiviral immunity. Here the authors show that chronic hepatitis C virus infection in human can imprint lasting functional phenotypes in NK cells to increase their inter-individual but decrease intra-individual diversity.

Bibliographic Details
Main Authors:	Benedikt Strunz, Julia Hengst, Katja Deterding, Michael P. Manns, Markus Cornberg, Hans-Gustaf Ljunggren, Heiner Wedemeyer, Niklas K. Björkström
Format:	Article
Language:	English
Published:	Nature Portfolio 2018-06-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-018-04685-9

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