Severe Stenosis of Mitral Bioprosthetic Valve Thrombosis in a Patient with HCV-Related Cirrhosis and Duodenal Variceal Bleeding: The Deadly Triad

Bioprosthetic valve thrombosis (BPVT) is considered a relatively rare but life-threatening clinical entity. Thus, there is the need of high clinical suspicion in order to make a timely diagnosis and related appropriate therapeutic interventions. In this regard, the management of BPVT is high risk, w...

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Main Authors: Rosangela Cocchia, Salvatore Chianese, Giovanni Lombardi, Luigia Romano, Valentina Capone, Lucio Amitrano, Raffaele Bennato, Brigida Ranieri, Giuseppe Russo, Ciro Mauro, Eduardo Bossone
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Clinics and Practice
Subjects:
Online Access:https://www.mdpi.com/2039-7283/12/5/71
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author Rosangela Cocchia
Salvatore Chianese
Giovanni Lombardi
Luigia Romano
Valentina Capone
Lucio Amitrano
Raffaele Bennato
Brigida Ranieri
Giuseppe Russo
Ciro Mauro
Eduardo Bossone
author_facet Rosangela Cocchia
Salvatore Chianese
Giovanni Lombardi
Luigia Romano
Valentina Capone
Lucio Amitrano
Raffaele Bennato
Brigida Ranieri
Giuseppe Russo
Ciro Mauro
Eduardo Bossone
author_sort Rosangela Cocchia
collection DOAJ
description Bioprosthetic valve thrombosis (BPVT) is considered a relatively rare but life-threatening clinical entity. Thus, there is the need of high clinical suspicion in order to make a timely diagnosis and related appropriate therapeutic interventions. In this regard, the management of BPVT is high risk, whatever the option taken (surgery and/or systemic fibrinolysis). The presence of severe comorbidities—as decompensated cirrhosis—further complicates the clinical decision-making process, calling for a patient-tailored integrated multidisciplinary approach. We report a challenging case of a 45-year-old patient with mitral bioprosthetic valve thrombosis and hepatitis C virus (HCV)-related cirrhosis complicated by active duodenal variceal bleeding.
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spelling doaj.art-7569553d9e784418b644723740a1bd2f2023-11-23T23:34:53ZengMDPI AGClinics and Practice2039-72832022-08-0112568669110.3390/clinpract12050071Severe Stenosis of Mitral Bioprosthetic Valve Thrombosis in a Patient with HCV-Related Cirrhosis and Duodenal Variceal Bleeding: The Deadly TriadRosangela Cocchia0Salvatore Chianese1Giovanni Lombardi2Luigia Romano3Valentina Capone4Lucio Amitrano5Raffaele Bennato6Brigida Ranieri7Giuseppe Russo8Ciro Mauro9Eduardo Bossone10Cardiology Unit, Antonio Cardarelli Hospital, 80131 Naples, ItalyCardiology Unit, Antonio Cardarelli Hospital, 80131 Naples, ItalyGastroenterology Unit, Antonio Cardarelli Hospital, 80131 Naples, ItalyDepartment of General and Emergency Radiology, Antonio Cardarelli Hospital, 80131 Naples, ItalyCardiology Unit, Antonio Cardarelli Hospital, 80131 Naples, ItalyGastroenterology Unit, Antonio Cardarelli Hospital, 80131 Naples, ItalyGastroenterology Unit, Antonio Cardarelli Hospital, 80131 Naples, ItalyIRCCS SYNLAB SDN, Via Emanuele Gianturco, 80143 Naples, ItalyChief Medical Officer, Antonio Cardarelli Hospital, 80131 Naples, ItalyCardiology Unit, Antonio Cardarelli Hospital, 80131 Naples, ItalyCardiology Unit, Antonio Cardarelli Hospital, 80131 Naples, ItalyBioprosthetic valve thrombosis (BPVT) is considered a relatively rare but life-threatening clinical entity. Thus, there is the need of high clinical suspicion in order to make a timely diagnosis and related appropriate therapeutic interventions. In this regard, the management of BPVT is high risk, whatever the option taken (surgery and/or systemic fibrinolysis). The presence of severe comorbidities—as decompensated cirrhosis—further complicates the clinical decision-making process, calling for a patient-tailored integrated multidisciplinary approach. We report a challenging case of a 45-year-old patient with mitral bioprosthetic valve thrombosis and hepatitis C virus (HCV)-related cirrhosis complicated by active duodenal variceal bleeding.https://www.mdpi.com/2039-7283/12/5/71bioprosthetic mitral valve thrombosisHCV-related cirrhosisduodenal variceal bleeding
spellingShingle Rosangela Cocchia
Salvatore Chianese
Giovanni Lombardi
Luigia Romano
Valentina Capone
Lucio Amitrano
Raffaele Bennato
Brigida Ranieri
Giuseppe Russo
Ciro Mauro
Eduardo Bossone
Severe Stenosis of Mitral Bioprosthetic Valve Thrombosis in a Patient with HCV-Related Cirrhosis and Duodenal Variceal Bleeding: The Deadly Triad
Clinics and Practice
bioprosthetic mitral valve thrombosis
HCV-related cirrhosis
duodenal variceal bleeding
title Severe Stenosis of Mitral Bioprosthetic Valve Thrombosis in a Patient with HCV-Related Cirrhosis and Duodenal Variceal Bleeding: The Deadly Triad
title_full Severe Stenosis of Mitral Bioprosthetic Valve Thrombosis in a Patient with HCV-Related Cirrhosis and Duodenal Variceal Bleeding: The Deadly Triad
title_fullStr Severe Stenosis of Mitral Bioprosthetic Valve Thrombosis in a Patient with HCV-Related Cirrhosis and Duodenal Variceal Bleeding: The Deadly Triad
title_full_unstemmed Severe Stenosis of Mitral Bioprosthetic Valve Thrombosis in a Patient with HCV-Related Cirrhosis and Duodenal Variceal Bleeding: The Deadly Triad
title_short Severe Stenosis of Mitral Bioprosthetic Valve Thrombosis in a Patient with HCV-Related Cirrhosis and Duodenal Variceal Bleeding: The Deadly Triad
title_sort severe stenosis of mitral bioprosthetic valve thrombosis in a patient with hcv related cirrhosis and duodenal variceal bleeding the deadly triad
topic bioprosthetic mitral valve thrombosis
HCV-related cirrhosis
duodenal variceal bleeding
url https://www.mdpi.com/2039-7283/12/5/71
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