Anti-infective Properties of the Golden Spice Curcumin
The search for novel anti-infectives is one of the most important challenges in natural product research, as diseases caused by bacteria, viruses, and fungi are influencing the human society all over the world. Natural compounds are a continuing source of novel anti-infectives. Accordingly, curcumin...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-05-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fmicb.2019.00912/full |
| _version_ | 1828846007597662208 |
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| author | Dimas Praditya Dimas Praditya Dimas Praditya Lisa Kirchhoff Janina Brüning Heni Rachmawati Heni Rachmawati Joerg Steinmann Joerg Steinmann Eike Steinmann |
| author_facet | Dimas Praditya Dimas Praditya Dimas Praditya Lisa Kirchhoff Janina Brüning Heni Rachmawati Heni Rachmawati Joerg Steinmann Joerg Steinmann Eike Steinmann |
| author_sort | Dimas Praditya |
| collection | DOAJ |
| description | The search for novel anti-infectives is one of the most important challenges in natural product research, as diseases caused by bacteria, viruses, and fungi are influencing the human society all over the world. Natural compounds are a continuing source of novel anti-infectives. Accordingly, curcumin, has been used for centuries in Asian traditional medicine to treat various disorders. Numerous studies have shown that curcumin possesses a wide spectrum of biological and pharmacological properties, acting, for example, as anti-inflammatory, anti-angiogenic and anti-neoplastic, while no toxicity is associated with the compound. Recently, curcumin’s antiviral and antibacterial activity was investigated, and it was shown to act against various important human pathogens like the influenza virus, hepatitis C virus, HIV and strains of Staphylococcus, Streptococcus, and Pseudomonas. Despite the potency, curcumin has not yet been approved as a therapeutic antiviral agent. This review summarizes the current knowledge and future perspectives of the antiviral, antibacterial, and antifungal effects of curcumin. |
| first_indexed | 2024-12-12T21:40:21Z |
| format | Article |
| id | doaj.art-756fb163b14e4f89bbb1a5da666fe24d |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-12T21:40:21Z |
| publishDate | 2019-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-756fb163b14e4f89bbb1a5da666fe24d2022-12-22T00:11:04ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2019-05-011010.3389/fmicb.2019.00912438961Anti-infective Properties of the Golden Spice CurcuminDimas Praditya0Dimas Praditya1Dimas Praditya2Lisa Kirchhoff3Janina Brüning4Heni Rachmawati5Heni Rachmawati6Joerg Steinmann7Joerg Steinmann8Eike Steinmann9Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, GermanyInstitute of Experimental Virology, Twincore – Centre for Experimental and Clinical Infection Research, A Joint Venture Between the Medical School Hannover and The Helmholtz Centre for Infection Research, Hanover, GermanyResearch Center for Biotechnology, Indonesian Institute of Science, Cibinong, IndonesiaInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen, GermanyDepartment of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, GermanySchool of Pharmacy, Bandung Institute of Technology, Bandung, IndonesiaResearch Center for Nanosciences and Nanotechnology, Bandung Institute of Technology, Bandung, IndonesiaInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen, GermanyInstitute of Clinical Hygiene, Medical Microbiology and Infectiology, Klinikum Nürnberg, Paracelsus Medical University, Nuremberg, GermanyDepartment of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, GermanyThe search for novel anti-infectives is one of the most important challenges in natural product research, as diseases caused by bacteria, viruses, and fungi are influencing the human society all over the world. Natural compounds are a continuing source of novel anti-infectives. Accordingly, curcumin, has been used for centuries in Asian traditional medicine to treat various disorders. Numerous studies have shown that curcumin possesses a wide spectrum of biological and pharmacological properties, acting, for example, as anti-inflammatory, anti-angiogenic and anti-neoplastic, while no toxicity is associated with the compound. Recently, curcumin’s antiviral and antibacterial activity was investigated, and it was shown to act against various important human pathogens like the influenza virus, hepatitis C virus, HIV and strains of Staphylococcus, Streptococcus, and Pseudomonas. Despite the potency, curcumin has not yet been approved as a therapeutic antiviral agent. This review summarizes the current knowledge and future perspectives of the antiviral, antibacterial, and antifungal effects of curcumin.https://www.frontiersin.org/article/10.3389/fmicb.2019.00912/fullcurcuminnatural productsnutraceuticalanti-infective propertiesvirusbacteria |
| spellingShingle | Dimas Praditya Dimas Praditya Dimas Praditya Lisa Kirchhoff Janina Brüning Heni Rachmawati Heni Rachmawati Joerg Steinmann Joerg Steinmann Eike Steinmann Anti-infective Properties of the Golden Spice Curcumin Frontiers in Microbiology curcumin natural products nutraceutical anti-infective properties virus bacteria |
| title | Anti-infective Properties of the Golden Spice Curcumin |
| title_full | Anti-infective Properties of the Golden Spice Curcumin |
| title_fullStr | Anti-infective Properties of the Golden Spice Curcumin |
| title_full_unstemmed | Anti-infective Properties of the Golden Spice Curcumin |
| title_short | Anti-infective Properties of the Golden Spice Curcumin |
| title_sort | anti infective properties of the golden spice curcumin |
| topic | curcumin natural products nutraceutical anti-infective properties virus bacteria |
| url | https://www.frontiersin.org/article/10.3389/fmicb.2019.00912/full |
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