A cellular and proteomic approach to assess proteins extracted from cryopreserved human amnion in the cultivation of corneal stromal keratocytes for stromal cell therapy

A cellular and proteomic approach to assess proteins extracted from cryopreserved human amnion in the cultivation of corneal stromal keratocytes for stromal cell therapy

Abstract Background Human corneal stromal keratocytes propagated in culture media supplemented with human amnion extract (AME) can correct early corneal haze in an animal model. Clinical application of cultivated keratocytes is limited by infectious disease screening before amnion products can be us...

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Bibliographic Details
Main Authors: Beau J. Fenner, Nur Zahirah B. M. Yusoff, Matthias Fuest, Lei Zhou, Francisco Bandeira, Howard Y. Cajucom-Uy, H. K. Tan, Jodhbir S. Mehta, Gary H. F. Yam
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Eye and Vision
Subjects:
Amnion extract
Proteomics
Corneal stromal keratocytes
Marker expression
Online Access:http://link.springer.com/article/10.1186/s40662-019-0155-0

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