Recent Advances of Macromolecular Hydrogels for Enzyme Immobilization in the Food Products

Enzymes are one of the main biocatalysts with various applications in the food industry. Stabilization of enzymes on insoluble carriers is important due to the low reuse, low operational stability, and high cost in applications. The immobility and the type of carrier affect the activity of the immob...

Full description

Bibliographic Details
Main Authors: Leila Yavari Maroufi, Mohsen Rashidi, Mahnaz Tabibiazar, Maryam Mohammadi, Akram Pezeshki, Marjan Ghorbani
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2022-03-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-12-309.pdf
_version_ 1818271773079109632
author Leila Yavari Maroufi
Mohsen Rashidi
Mahnaz Tabibiazar
Maryam Mohammadi
Akram Pezeshki
Marjan Ghorbani
author_facet Leila Yavari Maroufi
Mohsen Rashidi
Mahnaz Tabibiazar
Maryam Mohammadi
Akram Pezeshki
Marjan Ghorbani
author_sort Leila Yavari Maroufi
collection DOAJ
description Enzymes are one of the main biocatalysts with various applications in the food industry. Stabilization of enzymes on insoluble carriers is important due to the low reuse, low operational stability, and high cost in applications. The immobility and the type of carrier affect the activity of the immobile enzyme. Hydrogels are three-dimensionally cross-linked macromolecular network structures designed from various polymers. Hydrogels can provide a matrix for an immobile enzyme due to their extraordinary properties such as high water absorbing capacity, carrier of bioactive substances and enzymes, biocompatibility, safety, and biodegradability. Therefore, this study mainly focuses on some enzymes (lactase, lipases, amylases, pectinase, protease, glucose oxidase) that are of special importance in the food industry. These enzymes could be immobilized in the hydrogels constructed of macromolecules such as kappa-carrageenan, chitosan, Arabic gum, pectin, alginate, and cellulose. At last, in the preparation of these hydrogels, different enzyme immobilization methods in macromolecular hydrogels, and effect of hydrogels on enzyme activity were discussed.
first_indexed 2024-12-12T21:31:30Z
format Article
id doaj.art-75773fbb70104b3880f8c13628b45531
institution Directory Open Access Journal
issn 2228-5881
2251-7308
language English
last_indexed 2024-12-12T21:31:30Z
publishDate 2022-03-01
publisher Tabriz University of Medical Sciences
record_format Article
series Advanced Pharmaceutical Bulletin
spelling doaj.art-75773fbb70104b3880f8c13628b455312022-12-22T00:11:19ZengTabriz University of Medical SciencesAdvanced Pharmaceutical Bulletin2228-58812251-73082022-03-0112230931810.34172/apb.2022.043apb-32162Recent Advances of Macromolecular Hydrogels for Enzyme Immobilization in the Food ProductsLeila Yavari Maroufi0Mohsen Rashidi1Mahnaz Tabibiazar2Maryam Mohammadi3Akram Pezeshki4Marjan Ghorbani5Department of Food Science and Technology, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran.Department of Pharmacology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.Department of Food Science and Technology, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran.Department of Food Science and Technology, Faculty of Agriculture, University of Tabriz, Tabriz, Iran.Department of Food Science and Technology, Faculty of Agriculture, University of Tabriz, Tabriz, Iran.Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.Enzymes are one of the main biocatalysts with various applications in the food industry. Stabilization of enzymes on insoluble carriers is important due to the low reuse, low operational stability, and high cost in applications. The immobility and the type of carrier affect the activity of the immobile enzyme. Hydrogels are three-dimensionally cross-linked macromolecular network structures designed from various polymers. Hydrogels can provide a matrix for an immobile enzyme due to their extraordinary properties such as high water absorbing capacity, carrier of bioactive substances and enzymes, biocompatibility, safety, and biodegradability. Therefore, this study mainly focuses on some enzymes (lactase, lipases, amylases, pectinase, protease, glucose oxidase) that are of special importance in the food industry. These enzymes could be immobilized in the hydrogels constructed of macromolecules such as kappa-carrageenan, chitosan, Arabic gum, pectin, alginate, and cellulose. At last, in the preparation of these hydrogels, different enzyme immobilization methods in macromolecular hydrogels, and effect of hydrogels on enzyme activity were discussed.https://apb.tbzmed.ac.ir/PDF/apb-12-309.pdfhydrogelsenzyme immobilizationfood industry
spellingShingle Leila Yavari Maroufi
Mohsen Rashidi
Mahnaz Tabibiazar
Maryam Mohammadi
Akram Pezeshki
Marjan Ghorbani
Recent Advances of Macromolecular Hydrogels for Enzyme Immobilization in the Food Products
Advanced Pharmaceutical Bulletin
hydrogels
enzyme immobilization
food industry
title Recent Advances of Macromolecular Hydrogels for Enzyme Immobilization in the Food Products
title_full Recent Advances of Macromolecular Hydrogels for Enzyme Immobilization in the Food Products
title_fullStr Recent Advances of Macromolecular Hydrogels for Enzyme Immobilization in the Food Products
title_full_unstemmed Recent Advances of Macromolecular Hydrogels for Enzyme Immobilization in the Food Products
title_short Recent Advances of Macromolecular Hydrogels for Enzyme Immobilization in the Food Products
title_sort recent advances of macromolecular hydrogels for enzyme immobilization in the food products
topic hydrogels
enzyme immobilization
food industry
url https://apb.tbzmed.ac.ir/PDF/apb-12-309.pdf
work_keys_str_mv AT leilayavarimaroufi recentadvancesofmacromolecularhydrogelsforenzymeimmobilizationinthefoodproducts
AT mohsenrashidi recentadvancesofmacromolecularhydrogelsforenzymeimmobilizationinthefoodproducts
AT mahnaztabibiazar recentadvancesofmacromolecularhydrogelsforenzymeimmobilizationinthefoodproducts
AT maryammohammadi recentadvancesofmacromolecularhydrogelsforenzymeimmobilizationinthefoodproducts
AT akrampezeshki recentadvancesofmacromolecularhydrogelsforenzymeimmobilizationinthefoodproducts
AT marjanghorbani recentadvancesofmacromolecularhydrogelsforenzymeimmobilizationinthefoodproducts