Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years

Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years

BackgroundHuman perinatal life is characterized by a period of extraordinary change during which newborns encounter abundant environmental stimuli and exposure to potential pathogens. To meet such challenges, the neonatal immune system is equipped with unique functional characteristics that adapt to...

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Bibliographic Details
Main Authors:	James F. Read, Michael Serralha, Jesse D. Armitage, Muhammad Munir Iqbal, Mark N. Cruickshank, Alka Saxena, Deborah H. Strickland, Jason Waithman, Patrick G. Holt, Anthony Bosco
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-10-01
Series:	Frontiers in Immunology
Subjects:	single cell genomics scRNA-Seq toll-like receptors lipopolysaccharide poly(I:C) interferon
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1275937/full

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