Systems Biology Reveals S-Nitrosylation-Dependent Regulation of Mitochondrial Functions in Mice with <i>Shank3</i> Mutation Associated with Autism Spectrum Disorder

Systems Biology Reveals S-Nitrosylation-Dependent Regulation of Mitochondrial Functions in Mice with <i>Shank3</i> Mutation Associated with Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental disorder manifested in repetitive behavior, abnormalities in social interactions, and communication. The pathogenesis of this disorder is not clear, and no effective treatment is currently available. Protein S-nitrosylation (SNO), the nitric oxi...

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Bibliographic Details
Main Authors: Maryam Kartawy, Igor Khaliulin, Haitham Amal
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Brain Sciences
Subjects:
autism spectrum disorder
nitric oxide
S-nitrosylation
proteomics mitochondria
systems biology
Online Access:https://www.mdpi.com/2076-3425/11/6/677

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