Relationship between meteorological factors, air pollutants and hand, foot and mouth disease from 2014 to 2020
Abstract Background Meteorological factors and air pollutants have been reported to be associated with hand, foot, and mouth disease (HFMD) epidemics before the introduction of vaccine. However, there is limited evidence for studies with long-term dimensions. Methods We collected the daily HFMD coun...
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| Format: | Article |
| Language: | English |
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BMC
2022-05-01
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| Series: | BMC Public Health |
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| Online Access: | https://doi.org/10.1186/s12889-022-13365-9 |
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| author | Hongxia Peng Zhenhua Chen Lin Cai Juan Liao Ke Zheng Shuo Li Xueling Ren Xiaoxia Duan Xueqin Tang Xiao Wang Lu Long Chunxia Yang |
| author_facet | Hongxia Peng Zhenhua Chen Lin Cai Juan Liao Ke Zheng Shuo Li Xueling Ren Xiaoxia Duan Xueqin Tang Xiao Wang Lu Long Chunxia Yang |
| author_sort | Hongxia Peng |
| collection | DOAJ |
| description | Abstract Background Meteorological factors and air pollutants have been reported to be associated with hand, foot, and mouth disease (HFMD) epidemics before the introduction of vaccine. However, there is limited evidence for studies with long-term dimensions. Methods We collected the daily HFMD counts, weather and air pollution data from 2014 to 2020 in Chengdu. Distributed lag non-linear models (DLNM) were used to assess the associations of meteorological factors and air pollutants on HFMD cases. Results From 2014–2020, high relative humidity and precipitation and extremely high and low levels of PM10, O3, SO2 and CO increased the risk of HFMD. In pre-vaccination period, extreme high and low temperatures, PM10 and NO2, low precipitation and high concentrations of PM2.5 and O3 significantly increase the risk of HFMD; In post-vaccination period, high relative humidity and low level of CO can significantly increase the incidence of HFMD; During the period of COVID-19, only low temperature will significantly increase the risk of HFMD; Low concentration of air pollutants has the greatest impact on the 6–14 age group, while the high concentration of air pollutants has the greatest impact on the 0–1 age group. Conclusions Our study suggest that high relative humidity and precipitation and extremely high and low levels of PM10, O3, SO2 and CO increased the risk of HFMD from 2014 to 2020. The results of this study provide a reference for local authorities to formulate intervention measures and establish an environment-based disease early warning system. |
| first_indexed | 2024-12-12T08:23:06Z |
| format | Article |
| id | doaj.art-757abbb5b4724e7dac965ec11f53c64f |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-12-12T08:23:06Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-757abbb5b4724e7dac965ec11f53c64f2022-12-22T00:31:20ZengBMCBMC Public Health1471-24582022-05-0122111010.1186/s12889-022-13365-9Relationship between meteorological factors, air pollutants and hand, foot and mouth disease from 2014 to 2020Hongxia Peng0Zhenhua Chen1Lin Cai2Juan Liao3Ke Zheng4Shuo Li5Xueling Ren6Xiaoxia Duan7Xueqin Tang8Xiao Wang9Lu Long10Chunxia Yang11Department of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Microbiology Laboratory, Chengdu Municipal Center for Disease Control and PreventionDepartment of Gastroenterology, West China School of Public Health and West China Forth Hospital, Sichuan UniversityDepartment of Gastroenterology, West China School of Public Health and West China Forth Hospital, Sichuan UniversityDepartment of Immunization Planning, Chengdu Municipal Center for Disease Control and PreventionDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityAbstract Background Meteorological factors and air pollutants have been reported to be associated with hand, foot, and mouth disease (HFMD) epidemics before the introduction of vaccine. However, there is limited evidence for studies with long-term dimensions. Methods We collected the daily HFMD counts, weather and air pollution data from 2014 to 2020 in Chengdu. Distributed lag non-linear models (DLNM) were used to assess the associations of meteorological factors and air pollutants on HFMD cases. Results From 2014–2020, high relative humidity and precipitation and extremely high and low levels of PM10, O3, SO2 and CO increased the risk of HFMD. In pre-vaccination period, extreme high and low temperatures, PM10 and NO2, low precipitation and high concentrations of PM2.5 and O3 significantly increase the risk of HFMD; In post-vaccination period, high relative humidity and low level of CO can significantly increase the incidence of HFMD; During the period of COVID-19, only low temperature will significantly increase the risk of HFMD; Low concentration of air pollutants has the greatest impact on the 6–14 age group, while the high concentration of air pollutants has the greatest impact on the 0–1 age group. Conclusions Our study suggest that high relative humidity and precipitation and extremely high and low levels of PM10, O3, SO2 and CO increased the risk of HFMD from 2014 to 2020. The results of this study provide a reference for local authorities to formulate intervention measures and establish an environment-based disease early warning system.https://doi.org/10.1186/s12889-022-13365-9Hand, foot, and mouth diseaseMeteorological factorsAir pollutantsVaccinationCOVID-19 |
| spellingShingle | Hongxia Peng Zhenhua Chen Lin Cai Juan Liao Ke Zheng Shuo Li Xueling Ren Xiaoxia Duan Xueqin Tang Xiao Wang Lu Long Chunxia Yang Relationship between meteorological factors, air pollutants and hand, foot and mouth disease from 2014 to 2020 BMC Public Health Hand, foot, and mouth disease Meteorological factors Air pollutants Vaccination COVID-19 |
| title | Relationship between meteorological factors, air pollutants and hand, foot and mouth disease from 2014 to 2020 |
| title_full | Relationship between meteorological factors, air pollutants and hand, foot and mouth disease from 2014 to 2020 |
| title_fullStr | Relationship between meteorological factors, air pollutants and hand, foot and mouth disease from 2014 to 2020 |
| title_full_unstemmed | Relationship between meteorological factors, air pollutants and hand, foot and mouth disease from 2014 to 2020 |
| title_short | Relationship between meteorological factors, air pollutants and hand, foot and mouth disease from 2014 to 2020 |
| title_sort | relationship between meteorological factors air pollutants and hand foot and mouth disease from 2014 to 2020 |
| topic | Hand, foot, and mouth disease Meteorological factors Air pollutants Vaccination COVID-19 |
| url | https://doi.org/10.1186/s12889-022-13365-9 |
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