Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A.

Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A.

Endo-beta-N-acetylglucosaminidases (ENGases) are dual specificity enzymes with an ability to catalyze hydrolysis and transglycosylation reactions. Recently, these enzymes have become the focus of intense research because of their potential for synthesis of glycopeptides. We have determined the 3D st...

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Bibliographic Details
Main Authors: Jie Yin, Lei Li, Neil Shaw, Yang Li, Jing Katherine Song, Wenpeng Zhang, Chengfeng Xia, Rongguang Zhang, Andrzej Joachimiak, Hou-Cheng Zhang, Lai-Xi Wang, Zhi-Jie Liu, Peng Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2646837?pdf=render

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