Complex poisoning mainly with benzyl alcohol complicated by paralytic ileus: a case report

Abstract Background Benzyl alcohol is used as stripping agent in paints and other applications, and benzyl alcohol poisoning is indicated by symptoms, such as impaired consciousness, respiratory depression, hypotension, metabolic acidosis, and renal dysfunction. Case presentation A 27-year-old Asian...

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Main Authors: Hirotsugu Fukuda, Ryo Kamidani, Hideshi Okada, Yuichiro Kitagawa, Takahiro Yoshida, Shozo Yoshida, Shinji Ogura
Format: Article
Language:English
Published: BMC 2022-07-01
Series:International Journal of Emergency Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12245-022-00434-4
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author Hirotsugu Fukuda
Ryo Kamidani
Hideshi Okada
Yuichiro Kitagawa
Takahiro Yoshida
Shozo Yoshida
Shinji Ogura
author_facet Hirotsugu Fukuda
Ryo Kamidani
Hideshi Okada
Yuichiro Kitagawa
Takahiro Yoshida
Shozo Yoshida
Shinji Ogura
author_sort Hirotsugu Fukuda
collection DOAJ
description Abstract Background Benzyl alcohol is used as stripping agent in paints and other applications, and benzyl alcohol poisoning is indicated by symptoms, such as impaired consciousness, respiratory depression, hypotension, metabolic acidosis, and renal dysfunction. Case presentation A 27-year-old Asian man was transported to a hospital for severe disturbance of consciousness following exposure to a paint stripper containing benzyl alcohol, ethylene glycol, and hydrogen peroxide, which he was using to repaint a bridge. The patient was treated under sedation for benzyl alcohol poisoning. On day 3 of hospitalization, his abdominal computed tomography scan revealed a paralytic ileus, so he was transferred to our hospital. The combined toxicity from multiple substances, mainly benzyl alcohol, was thought to be a contributing factor for the paralytic ileus. Upon arrival, the patient also had chemical burns, hypernatremia, and elevated myogenic enzyme levels. His urinary hippuric acid level was high (14.9 g/L) upon admission to the previous hospital. We treated the patient with artificial respiration management, while avoiding high-density oxygen, and with gastrointestinal decompression by gastric tube implantation; laxatives were also administered. The paralytic ileus improved on the 4th day, the tube was removed on the 6th day, and the patient was discharged on the 11th day of hospitalization. No apparent complications were observed at discharge. Conclusions To the best of our knowledge, this is the first case report of paralytic ileus caused by benzyl alcohol, although multiple factors may have influenced the symptoms. After exposure to benzyl alcohol by inhalation and dermal absorption, the patient developed impaired consciousness, metabolic acidosis, and paralytic ileus, and the presence of elevated urinary hippuric acid led to a definitive diagnosis.
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spelling doaj.art-75816b13daf54658a0628ed173b497fb2022-12-22T02:44:08ZengBMCInternational Journal of Emergency Medicine1865-13721865-13802022-07-011511610.1186/s12245-022-00434-4Complex poisoning mainly with benzyl alcohol complicated by paralytic ileus: a case reportHirotsugu Fukuda0Ryo Kamidani1Hideshi Okada2Yuichiro Kitagawa3Takahiro Yoshida4Shozo Yoshida5Shinji Ogura6Department of Emergency and Disaster Medicine, Gifu University Graduate School of MedicineDepartment of Emergency and Disaster Medicine, Gifu University Graduate School of MedicineDepartment of Emergency and Disaster Medicine, Gifu University Graduate School of MedicineDepartment of Emergency and Disaster Medicine, Gifu University Graduate School of MedicineDepartment of Emergency and Disaster Medicine, Gifu University Graduate School of MedicineDepartment of Emergency and Disaster Medicine, Gifu University Graduate School of MedicineDepartment of Emergency and Disaster Medicine, Gifu University Graduate School of MedicineAbstract Background Benzyl alcohol is used as stripping agent in paints and other applications, and benzyl alcohol poisoning is indicated by symptoms, such as impaired consciousness, respiratory depression, hypotension, metabolic acidosis, and renal dysfunction. Case presentation A 27-year-old Asian man was transported to a hospital for severe disturbance of consciousness following exposure to a paint stripper containing benzyl alcohol, ethylene glycol, and hydrogen peroxide, which he was using to repaint a bridge. The patient was treated under sedation for benzyl alcohol poisoning. On day 3 of hospitalization, his abdominal computed tomography scan revealed a paralytic ileus, so he was transferred to our hospital. The combined toxicity from multiple substances, mainly benzyl alcohol, was thought to be a contributing factor for the paralytic ileus. Upon arrival, the patient also had chemical burns, hypernatremia, and elevated myogenic enzyme levels. His urinary hippuric acid level was high (14.9 g/L) upon admission to the previous hospital. We treated the patient with artificial respiration management, while avoiding high-density oxygen, and with gastrointestinal decompression by gastric tube implantation; laxatives were also administered. The paralytic ileus improved on the 4th day, the tube was removed on the 6th day, and the patient was discharged on the 11th day of hospitalization. No apparent complications were observed at discharge. Conclusions To the best of our knowledge, this is the first case report of paralytic ileus caused by benzyl alcohol, although multiple factors may have influenced the symptoms. After exposure to benzyl alcohol by inhalation and dermal absorption, the patient developed impaired consciousness, metabolic acidosis, and paralytic ileus, and the presence of elevated urinary hippuric acid led to a definitive diagnosis.https://doi.org/10.1186/s12245-022-00434-4Benzyl alcohol poisoningParalytic ileusPoisoningHydrogen peroxideCase report
spellingShingle Hirotsugu Fukuda
Ryo Kamidani
Hideshi Okada
Yuichiro Kitagawa
Takahiro Yoshida
Shozo Yoshida
Shinji Ogura
Complex poisoning mainly with benzyl alcohol complicated by paralytic ileus: a case report
International Journal of Emergency Medicine
Benzyl alcohol poisoning
Paralytic ileus
Poisoning
Hydrogen peroxide
Case report
title Complex poisoning mainly with benzyl alcohol complicated by paralytic ileus: a case report
title_full Complex poisoning mainly with benzyl alcohol complicated by paralytic ileus: a case report
title_fullStr Complex poisoning mainly with benzyl alcohol complicated by paralytic ileus: a case report
title_full_unstemmed Complex poisoning mainly with benzyl alcohol complicated by paralytic ileus: a case report
title_short Complex poisoning mainly with benzyl alcohol complicated by paralytic ileus: a case report
title_sort complex poisoning mainly with benzyl alcohol complicated by paralytic ileus a case report
topic Benzyl alcohol poisoning
Paralytic ileus
Poisoning
Hydrogen peroxide
Case report
url https://doi.org/10.1186/s12245-022-00434-4
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