Biological Actions of the Hsp90-binding Immunophilins FKBP51 and FKBP52
Immunophilins are a family of proteins whose signature domain is the peptidylprolyl-isomerase domain. High molecular weight immunophilins are characterized by the additional presence of tetratricopeptide-repeats (TPR) through which they bind to the 90-kDa heat-shock protein (Hsp90), and via this cha...
Main Authors: | Nadia R. Zgajnar, Sonia A. De Leo, Cecilia M. Lotufo, Alejandra G. Erlejman, Graciela Piwien-Pilipuk, Mario D. Galigniana |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-02-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/9/2/52 |
Similar Items
-
The Scaffold Immunophilin FKBP51 Is a Phosphoprotein That Undergoes Dynamic Mitochondrial-Nuclear Shuttling
by: Nadia R. Zgajnar, et al.
Published: (2022-11-01) -
The Many Faces of FKBP51
by: Andreas Hähle, et al.
Published: (2019-01-01) -
FKBP Ligands—Where We Are and Where to Go?
by: Jürgen M. Kolos, et al.
Published: (2018-12-01) -
Pharmacological Modulation of the Psychiatric Risk Factor FKBP51 Alters Efficiency of Common Antidepressant Drugs
by: Max L. Pöhlmann, et al.
Published: (2018-11-01) -
FKBP51 increases the tumour‐promoter potential of TGF‐beta
by: Simona Romano, et al.
Published: (2014-12-01)