The Prevalence of <i>Chlamydia trachomatis</i> and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania

Efforts to map the burden of infections globally have shown a high prevalence of genital infections, including <i>Chlamydia trachomatis</i>, in sub-Saharan Africa. This retrospective study aimed to investigate the prevalence of selected non-viral genital infections among pregnant women i...

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Main Authors: Naomi C.A. Juliana, Saikat Deb, Sander Ouburg, Aishwarya Chauhan, Jolein Pleijster, Said M. Ali, Servaas A. Morré, Sunil Sazawal, Elena Ambrosino
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/9/8/625
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author Naomi C.A. Juliana
Saikat Deb
Sander Ouburg
Aishwarya Chauhan
Jolein Pleijster
Said M. Ali
Servaas A. Morré
Sunil Sazawal
Elena Ambrosino
author_facet Naomi C.A. Juliana
Saikat Deb
Sander Ouburg
Aishwarya Chauhan
Jolein Pleijster
Said M. Ali
Servaas A. Morré
Sunil Sazawal
Elena Ambrosino
author_sort Naomi C.A. Juliana
collection DOAJ
description Efforts to map the burden of infections globally have shown a high prevalence of genital infections, including <i>Chlamydia trachomatis</i>, in sub-Saharan Africa. This retrospective study aimed to investigate the prevalence of selected non-viral genital infections among pregnant women in Pemba Island, Tanzania. Vaginal swabs were collected during pregnancy and stored in eNAT buffer. Detection of <i>C. trachomatis</i>, <i>Neisseria gonorrheae</i>, <i>Trichomonas vaginalis</i>, and <i>Mycoplasma genitalium</i> pathogens was performed by PCR using validated detection kits. Vaginal samples of 439 pregnant women between 16 and 48 years were tested. In fifty-five (12.5%) of them, at least one genital pathogen was detected. The most prevalent pathogen was <i>T. vaginalis</i> (7.1%), followed by <i>C. trachomatis</i> (4.6%) and <i>M. genitalium</i> (2.1%). None of the vaginal samples tested positive for <i>N. gonorrheae</i>. Consequently, among positive samples, 7.3% were for <i>C. trachomatis</i> and at least one other genital pathogen. This study provides insights on the burden of the four studied genital infections, and on the coinfections among pregnant women in Pemba Island, Tanzania. These results offer a starting point that can be useful to design further research in the field of maternal and child health in Pemba Island.
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spelling doaj.art-75858537594249b9842807c7342fbdb12023-11-20T08:38:08ZengMDPI AGPathogens2076-08172020-07-019862510.3390/pathogens9080625The Prevalence of <i>Chlamydia trachomatis</i> and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island TanzaniaNaomi C.A. Juliana0Saikat Deb1Sander Ouburg2Aishwarya Chauhan3Jolein Pleijster4Said M. Ali5Servaas A. Morré6Sunil Sazawal7Elena Ambrosino8Institute for Public Health Genomics (IPHG), Department of Genetics and Cell Biology, Research School GROW (School for Oncology & Developmental Biology), Faculty of Health, Medicine & Life Sciences, University of Maastricht, 6229 ER Maastricht, The NetherlandsPublic Health Laboratory-Ivo de Carneri, Chake Chake, Pemba Island, TanzaniaLaboratory of Immunogenetics; Department of Medical Microbiology and Infection Control, Amsterdam UMC, Vrije Universiteit, 1105 AZ Amsterdam, The NetherlandsCentre for Public Health Kinetics, New Delhi 110024, IndiaLaboratory of Immunogenetics; Department of Medical Microbiology and Infection Control, Amsterdam UMC, Vrije Universiteit, 1105 AZ Amsterdam, The NetherlandsPublic Health Laboratory-Ivo de Carneri, Chake Chake, Pemba Island, TanzaniaInstitute for Public Health Genomics (IPHG), Department of Genetics and Cell Biology, Research School GROW (School for Oncology & Developmental Biology), Faculty of Health, Medicine & Life Sciences, University of Maastricht, 6229 ER Maastricht, The NetherlandsCentre for Public Health Kinetics, New Delhi 110024, IndiaInstitute for Public Health Genomics (IPHG), Department of Genetics and Cell Biology, Research School GROW (School for Oncology & Developmental Biology), Faculty of Health, Medicine & Life Sciences, University of Maastricht, 6229 ER Maastricht, The NetherlandsEfforts to map the burden of infections globally have shown a high prevalence of genital infections, including <i>Chlamydia trachomatis</i>, in sub-Saharan Africa. This retrospective study aimed to investigate the prevalence of selected non-viral genital infections among pregnant women in Pemba Island, Tanzania. Vaginal swabs were collected during pregnancy and stored in eNAT buffer. Detection of <i>C. trachomatis</i>, <i>Neisseria gonorrheae</i>, <i>Trichomonas vaginalis</i>, and <i>Mycoplasma genitalium</i> pathogens was performed by PCR using validated detection kits. Vaginal samples of 439 pregnant women between 16 and 48 years were tested. In fifty-five (12.5%) of them, at least one genital pathogen was detected. The most prevalent pathogen was <i>T. vaginalis</i> (7.1%), followed by <i>C. trachomatis</i> (4.6%) and <i>M. genitalium</i> (2.1%). None of the vaginal samples tested positive for <i>N. gonorrheae</i>. Consequently, among positive samples, 7.3% were for <i>C. trachomatis</i> and at least one other genital pathogen. This study provides insights on the burden of the four studied genital infections, and on the coinfections among pregnant women in Pemba Island, Tanzania. These results offer a starting point that can be useful to design further research in the field of maternal and child health in Pemba Island.https://www.mdpi.com/2076-0817/9/8/625<i>Chlamydia trachomatis</i><i>Neisseria gonorrhoeae</i><i>Trichomonas vaginalis</i><i>Mycoplasma genitalium</i>sexual and reproductive healthpregnancy
spellingShingle Naomi C.A. Juliana
Saikat Deb
Sander Ouburg
Aishwarya Chauhan
Jolein Pleijster
Said M. Ali
Servaas A. Morré
Sunil Sazawal
Elena Ambrosino
The Prevalence of <i>Chlamydia trachomatis</i> and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania
Pathogens
<i>Chlamydia trachomatis</i>
<i>Neisseria gonorrhoeae</i>
<i>Trichomonas vaginalis</i>
<i>Mycoplasma genitalium</i>
sexual and reproductive health
pregnancy
title The Prevalence of <i>Chlamydia trachomatis</i> and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania
title_full The Prevalence of <i>Chlamydia trachomatis</i> and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania
title_fullStr The Prevalence of <i>Chlamydia trachomatis</i> and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania
title_full_unstemmed The Prevalence of <i>Chlamydia trachomatis</i> and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania
title_short The Prevalence of <i>Chlamydia trachomatis</i> and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania
title_sort prevalence of i chlamydia trachomatis i and three other non viral sexually transmitted infections among pregnant women in pemba island tanzania
topic <i>Chlamydia trachomatis</i>
<i>Neisseria gonorrhoeae</i>
<i>Trichomonas vaginalis</i>
<i>Mycoplasma genitalium</i>
sexual and reproductive health
pregnancy
url https://www.mdpi.com/2076-0817/9/8/625
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